Primary Aldosteronism in Pregnancy
Primary aldosteronism (PA) is uncommon in pregnancy, with fewer than 64 cases reported in the medical literature; most of these reported patients had aldosterone-producing adenomas (APAs). PA can lead to…
The Peripartum Diagnosis of Pheochromocytoma and a Genetic Mystery Solved
As we have highlighted in the other cases, the clinical management of catecholamine-secreting pheochromocytomas or paragangliomas (PPGLs) can be very challenging—both diagnostically and therapeutically. However, when PPGL is diagnosed in…
Catecholamine-Secreting Paraganglioma in Pregnancy
As we have highlighted in the other cases, the clinical management of catecholamine-secreting pheochromocytomas or paragangliomas (PPGLs) can be challenging—both diagnostically and therapeutically. However, when PPGL is diagnosed in the…
Pregnancy in a Patient With 21-Hydroxylase Deficiency
The most common type of congenital adrenal hyperplasia (CAH) is 21-hydroxylase deficiency, which occurs in 1 in 10,000 live births. The goals of therapy in CAH include (1) replacement therapy…
Sorting Out the Source of Androgen Excess in a Postmenopausal Woman With an Adrenal Mass
Postmenopausal androgen hypersecretion may be due to an ovarian tumor, an adrenal tumor, or ovarian hyperthecosis. It is important to assess the patient with a full androgen profile and imaging…
Malignant Pheochromocytoma in Pregnancy
As we have highlighted in the other cases, the clinical management of catecholamine-secreting pheochromocytomas or paragangliomas (PPGLs) can be challenging—both diagnostically and therapeutically. However, when PPGL is diagnosed in the…
Pregnancy in a Patient With Primary Adrenal Insufficiency
Pregnancy is a state of physiologic hypercortisolism. Management of adrenal insufficiency during pregnancy includes adjustment of therapy to physiologic needs and avoidance of adrenal crisis through an in-depth education, availability,…
History of Pregnancy in a 41-Year-Old Woman With Undiagnosed Cushing Syndrome
Workup for corticotropin (ACTH)-independent hypercortisolism is required in any patient with an adrenal mass, regardless of symptoms of hormone excess. Unfortunately, only a minority of patients with adrenal incidentalomas undergo…
Testosterone-Secreting Benign Adrenal Adenoma in a Postmenopausal Woman
Androgen hypersecretion in postmenopausal women may be due to an ovarian tumor, an adrenal tumor, ovarian hyperthecosis, or nonclassic congenital adrenal hyperplasia. The expansiveness of the diagnostic evaluation of a…
Premenopausal Woman With Testosterone-Secreting Ovarian Tumor
Androgen hypersecretion in a premenopausal woman may be due to an ovarian tumor, an adrenal tumor, polycystic ovarian syndrome, or nonclassic congenital adrenal hyperplasia. The expansiveness of the diagnostic evaluation…
