Abstract In clinical practice, the use of preoperative or neoadjuvant chemotherapy for the treatment of inoperable and operable breast cancer is currently well established. Once reserved for the treatment of…
Abstract Mastectomy surgery has been historically judged by its success at preventing local failures after primary invasive breast cancer treatment. Advancements in the use of adjuvant systemic treatments have further…
Abstract Over the past 30 years, new and advanced breast cancer multimodality treatments have resulted in improved median survival times for patients with metastatic breast cancer. Breast cancer most commonly…
Abstract Breast cancer is the most common cancer diagnosed in women in the United States. Approximately 12% of breast cancers are diagnosed in women younger than 44 years of age….
Abstract The importance of regional lymph nodes in breast cancer and their appropriate treatment has undergone dramatic changes in a relatively short period. Although oncologists once considered them the gold…
Abstract This chapter discusses the potential complications associated with the use of radiotherapy for breast cancer. These may occur in the weeks during or after radiation, such as fatigue or…
Abstract The advent of screening mammography and its widespread application has resulted in more patients being diagnosed with small invasive breast cancers. Most of these early breast cancer patients can…
Abstract Endocrine therapy is a key component of the adjuvant treatment of early-stage breast cancer. In this chapter, we review the current approach to adjuvant endocrine therapy for early-stage invasive…
Abstract This chapter describes the evolution of therapy for locally advanced breast cancer. Optimal management requires coordinated multidisciplinary care. Current treatment paradigms for LABC include use of neoadjuvant chemotherapy; resection,…
Abstract Background: While surgery is still the cornerstone treatment for early stage breast cancer, a deeper understanding in breast cancer biology has led to improvements in systemic therapies that improve…
