Molecular Pathology of Bone and Soft Tissue Neoplasms and Potential Targets for Novel Therapy

Jan 31, 2017 by in ONCOLOGY Comments Off on Molecular Pathology of Bone and Soft Tissue Neoplasms and Potential Targets for Novel Therapy

Neoplasm Translocation Gene/alteration Alveolar rhabdomyosarcoma t(2;13)(q35;q14) PAX3-FOXO1 t(1;13)(p36;q14) PAX7-FOXO1 t(X;2)(q13;q35) PAX3-AFX Alveolar soft part sarcoma der(17)t(X;17)(p11;q25) ASPL-TFE3 Angiomatoid fibrous histiocytoma t(12;22)(q13;q12) EWSR1-ATF1 t(2;22)(q33;q12) EWSR1-CREB1 t(12;16)(q13;p11) FUS-ATF1 Clear cell sarcoma t(12;22)(q13;q12)…

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Molecular Pathology and Diagnostics of Gliomas

Jan 31, 2017 by in ONCOLOGY Comments Off on Molecular Pathology and Diagnostics of Gliomas

   I II III IV Astrocytomas Pilocytic X    Diffuse  X   Anaplastic   X  Glioblastoma    X Gliosarcoma    X Oligodendroglial tumors Oligodendroglioma  X   Anaplastic oligodendroglioma   X  Mixed tumors Oligoastrocytoma  X   Anaplastic oligoastrocytoma   X …

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Molecular Pathology and Diagnostics of Prostate Cancer

Jan 31, 2017 by in ONCOLOGY Comments Off on Molecular Pathology and Diagnostics of Prostate Cancer

179. Quax PH, de Bart AC, Schalken JA, Verheijen JH (1997) Plasminogen activator and matrix metalloproteinase production and extracellular matrix degradation by rat prostate cancer cells in vitro: correlation with…

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Molecular Diagnostics of Pancreatic Cancer

Jan 31, 2017 by in ONCOLOGY Comments Off on Molecular Diagnostics of Pancreatic Cancer

11. Kloppel G, Kosmahl M, Luttges J (2005) Intraductal neoplasms of the pancreas: cystic and common. Pathologe 26(1):31–36PubMed 12. Canto MI et al (2004) Screening for pancreatic neoplasia in high-risk…

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Molecular Pathology and Diagnostics of Breast Cancer

Jan 31, 2017 by in ONCOLOGY Comments Off on Molecular Pathology and Diagnostics of Breast Cancer

Fig. 3.1 Murine mammary gland development. (a) During embryonic development, bilateral milk lines are established by embryonic day 10 (E10). The milk line breaks up and coalesces into individual mammary…

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Medullary Thyroid Cancer

Jan 31, 2017 by in ONCOLOGY Comments Off on Medullary Thyroid Cancer

Fig. 8.1 Calcitonin stain showing C-cell hyperplasia (Courtesy of Dr Moosa Khalil) MTCs are most frequently located posteriorly at the junction between the upper-third and lower two-thirds of the lateral…

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