Kaposi Sarcoma
Chapter 59 Kaposi Sarcoma Susan E. Krown, MD Kaposi sarcoma (KS) was one of the first opportunistic diseases described in association with the acquired immune deficiency syndrome (AIDS).1 Despite a…
Mycoses Caused by Molds
Chapter 47 Mycoses Caused by Molds Thomas F. Patterson, MD, John R. Graybill, MD Infections caused by molds are uncommon but important causes of opportunistic infections in patients with advanced…
Fosamprenavir and Amprenavir
Chapter 19 Fosamprenavir and Amprenavir Roger Paredes, MD, Lidia Ruiz, PhD, Bonaventura Clotet, MD, PhD INTRODUCTION Protease inhibitors (PIs) are one of the mainstays of HIV/AIDS therapy,1 being largely responsible…
Cryptococcosis
Chapter 43 Cryptococcosis Judith A. Aberg, MD, William G. Powderly, MD Disseminated cryptococcosis has been the most common life-threatening fungal infection in patients with acquired immunodeficiency syndrome (AIDS), affecting up…
Herpes Simplex Virus Infections
Chapter 48 Herpes Simplex Virus Infections Kimberly Y. Smith, MD, MPH, Harold A. Kessler, MD PATHOGEN Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are common pathogens in…
Coccidioidomycosis
Chapter 45 Coccidioidomycosis Neil M. Ampel, MD INTRODUCTION Coccidioidomycosis is an infection caused by the dimorphic fungus Coccidioides. The endemic region for this mycosis is confined to the Western hemisphere…
Saquinavir
Chapter 15 Saquinavir Anton Posniak, MD, FRCP, Kasha P. Singh, MBBS, FRACP INTRODUCTION On the 4 December 1997, the Society for Medicines Research Award for Drug Discovery was presented to…
Drug Interactions and Administration
Chapter 79 Drug Interactions and Administration Charles Flexner, MD, Paul A. Pham, PharmD Pharmacology plays a critical role in the treatment of HIV infection affecting issues as diverse as adherence,…
Abnormalities of Fat Distribution in HIV Infection
Chapter 73 Abnormalities of Fat Distribution in HIV Infection Carl Grunfeld, MD, PhD Shortly after the introduction of combination antiretroviral therapy with HIV protease inhibitors (PIs), changes in fat (Table…
