Introduction to Hypothyroidism
Introduction to Hypothyroidism Lewis E. Braverman David S. Cooper Hypothyroidism is the most common clinical disorder of thyroid function. It is most often caused by a disorder of the thyroid…
Subclinical Thyrotoxicosis
Subclinical Thyrotoxicosis Douglas S. Ross The introduction of serum thyrotropin (TSH) measurements into clinical practice during the early 1970s provided the necessary tool for defining subclinical hypothyroidism, although it took…
Treatment of Thyrotoxicosis
Treatment of Thyrotoxicosis David S. Cooper The ideal treatment of thyrotoxicosis would be directed at its cause. This is possible in only a few patients; e.g., those with exogenous thyrotoxicosis…
Diagnosis of Thyrotoxicosis
Diagnosis of Thyrotoxicosis Paul W. Ladenson Thyrotoxicosis often presents as a distinctive clinical syndrome readily confirmed by the findings of a low serum thyrotropin thyroid-stimulating hormone (TSH) concentration and high…
Thyrotoxic Storm
Thyrotoxic Storm Leonard Wartofsky Thyrotoxic storm or crisis is a rare, life-threatening syndrome characterized by exaggerated clinical manifestations of thyrotoxicosis (1). Its incidence is not precisely known because there are…
Behavioral and Psychiatric Aspects of Thyrotoxicosis
Behavioral and Psychiatric Aspects of Thyrotoxicosis Michael Bauer Mary H. Samuels Peter C. Whybrow When Parry first described the syndrome of hyperfunction of the thyroid gland in 1825, he attributed…
The Skeletal System in Thyrotoxicosis
The Skeletal System in Thyrotoxicosis Graham R. Williams Regulation of Thyroid Status Circulating thyroid hormone concentrations are maintained in the euthyroid range by the hypothalamic–pituitary–thyroid (HPT) axis, a classic example…
The Male and Female Reproductive System in Thyrotoxicosis
The Male and Female Reproductive System in Thyrotoxicosis Gerasimos E. Krassas Nikolaos E. Pontikides The reproductive system has been suggested to be relatively resistant to the effects of thyroid dysfunction….
Thyroid Hormones in Thermogenesis, Intermediary Metabolism, and Obesity
Thyroid Hormones in Thermogenesis, Intermediary Metabolism, and Obesity Thomas Reinehr Introduction Thyroid hormones can modulate numerous cellular processes that are relevant for thermogenesis, basal metabolic rate, and consequently for body…
The Cardiovascular System in Thyrotoxicosis
The Cardiovascular System in Thyrotoxicosis Irwin L. Klein Sara Danzi Almost two centuries ago, Caleb Parry, an English physician from Bath, reported on the association between thyrotoxicosis and the cardiovascular…
