Molecular Biology of Leukemias
Chromosomal translocations Genes Comments Involving RARAα t(15;17)(q21;q21) PML DNA binding, cell proliferation RARα Transcription factor t(11;17)(q23;q21) ZBTB16 (PLZF) Zn-finger transcription factor RARα Transcription factor t(5;17)(q32;q21) NPM1 RNA transport/processing RARα Transcription…