TREATMENT OF OBESITY Part of “CHAPTER 126 – OBESITY“ WEIGHT-REDUCTION MEASURES In most obese individuals, specific aberrations of the weight-control mechanism described under Pathogenesis cannot be identified and, thus, treatment…
ENDOCRINE AND METABOLIC CONSEQUENCES OF OBESITY Part of “CHAPTER 126 – OBESITY“ Various alterations in endocrine and metabolic function can be observed in obese individuals, including disturbances of growth hormone,…
ADIPOSE TISSUE GROWTH AND DEVELOPMENT Part of “CHAPTER 126 – OBESITY“ EARLY GROWTH OF ADIPOSE TISSUE Normal growth of human adipose tissue is achieved through an increase in adipocyte size…
PATHOGENESIS Part of “CHAPTER 126 – OBESITY“ THERMODYNAMIC CONSIDERATIONS It has become customary to remind all who deal with obesity that it is a disease of energy storage and as…
DEFINITION AND COMPLICATIONS OF OBESITY Part of “CHAPTER 126 – OBESITY“ DETERMINATION OF OBESITY Obesity is an excess of body fat (adipose tissue), and ideally the diagnosis should be based…
PREVALENCE OF OBESITY Part of “CHAPTER 126 – OBESITY“ An expert panel assembled by the National Institutes of Health (NIH) stated, “An estimated 97 million adults in the United States…
CLINICAL ABNORMALITIES OF APPETITE Part of “CHAPTER 125 – APPETITE“ KLEINE-LEVIN SYNDROME The Kleine-Levin syndrome (see Chap. 128) is a rare disease comprising periodic hypersomnia, hyperphagia, and abnormal behavior frequently…
CENTRAL EFFECTORS IN THE CONTROL OF APPETITE AND ENERGY HOMEOSTASIS Part of “CHAPTER 125 – APPETITE“ The hypothalamus contains many hormones and neuropeptides that are targets for peripheral signals. Some…
LONG-TERM REGULATION OF APPETITE AND ENERGY HOMEOSTASIS Part of “CHAPTER 125 – APPETITE“ Long-term regulation of appetite serves to compensate for temporary inadequacies in food intake and to control energy…
