Benign Hematology
Benign Hematology BIOLOGY OF HEMATOPOIESIS Anita Kumar Definition of Hematopoiesis: The formation of blood cells Sites of Hematopoiesis Bone marrow (BM) is the principal site of hematopoiesis in adults, predominantly…
Stem Cell Transplantation
Stem Cell Transplantation AUTOLOGOUS STEM CELL TRANSPLANTATION Amanda L. Olson Craig Sauter Description HDC/radiation followed by infusion of autologous multipotent hematopoietic stem cells. Tx of hematologic malignancies using HDC/radiation followed…
Leukemias and Myelodysplastic Syndromes
Leukemias and Myelodysplastic Syndromes MYELODYSPLASTIC SYNDROMES Justin M. Watts Virginia M. Klimek Epidemiology ˜10000 cases diagnosed annually in the United States Incidence >20/100000 in adults >70 y → actual incidence…
Myeloproliferative Disorders
Myeloproliferative Disorders ESSENTIAL THROMBOCYTHEMIA Raajit Rampal Clonal hematopoietic disorder resulting in ↑ red cell mass Epidemiology Incidence: Median age at dx is 60 y. 1/5 of pts under age 40…
Plasma Cell Disorders
Plasma Cell Disorders MGUS AND MULTIPLE MYELOMA (MM) Patrick W. Burke Hani Hassoun Definition Monoclonal gammopathy of undetermined significance (MGUS): Premalignancy w/clonal plasma cell (PC) proliferation. No e/o other B-cell…
Cancer of Unknown Primary
Cancer of Unknown Primary CANCER OF UNKNOWN PRIMARY (CUP) Jean K. Lee Lewis J. Kampel Overview & Epidemiology CUP, or occult 1° tumors: Histologically proven malignant tumors w/o an identified…
Neurologic Oncology
Neurologic Oncology ASTROCYTOMAS Parisa Momtaz Thomas J. Kaley Definition Astrocytoma is the most common type of gliomas Classified under a grading system: Grade 1 (typically benign), grade 2 (low-grade astrocytomas),…
Breast Cancer
Breast Cancer LOCALIZED BREAST CANCER Neil M. Iyengar Chau T. Dang Epidemiology Most common female malignancy & 2nd most common cause of CA death in the United States Approx. 225000…
Gynecologic Malignancies
Gynecologic Malignancies OVARIAN CANCER Juliana Eng Roisin O’Cearbhaill Epidemiology Ovarian CA is the leading cause of death from gyn CA in the United States 5th most common cause of CA…
