Cardiotoxicity of Cancer Therapy
Cardiotoxicity of Cancer Therapy Justin D. Floyd Michael C. Perry It is well recognized that antineoplastic agents may have adverse effects on multiple organs and normal tissues. The most commonly…
Ocular Side Effects of Cancer Therapeutics
Ocular Side Effects of Cancer Therapeutics Ravi Bobba Mark Klein The increased use of chemotherapeutic agents combined with longer patient survival has led to a higher incidence and recognition of…
Hypersensitivity Reactions
Hypersensitivity Reactions C. Daniel Kingsley Nearly all of the available chemotherapeutic agents can produce hypersensitivity reactions (HSRs) in at least an occasional patient, and some cause reactions in 5% or…
Extravasation
Extravasation Taher Abu Hejleh Gerald H. Clamon The accidental extravasation of chemotherapeutic agents during intravenous administration has been reported in approximately 0.1% to 6.0% of patients.1,2 Cancer patients may be…
Dermatologic Toxicity
Dermatologic Toxicity Susan K. Ailor Stacia C. Miles The ability of human skin to serve as a protector, a sensor, a temperature regulator, and an overall window into the body’s…
Oral Toxicity
Oral Toxicity Michael T. Brennan Rajesh V. Lalla Mark M. Schubert Douglas E. Peterson The oral cavity can be profoundly affected by cytotoxic chemotherapy used for the treatment of cancer….
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation Steven Z. Pavletic James O. Armitage Many effective cancer chemotherapeutic agents are destructive to the normal bone marrow cells. Therefore, bone marrow toxicity is often a…
Intraarterial Chemotherapy
Intraarterial Chemotherapy William D. Ensminger Intraarterial therapy is significantly more complex, difficult to correctly perform, and carries more risks than conventional standard systemic intravenous or oral therapy in the treatment…
Intraperitoneal Chemotherapy
Intraperitoneal Chemotherapy Maurie Markman The intraperitoneal administration of chemotherapeutic agents has evolved since the 1980s from a pharmacokinetic concept to a procedure that should be considered for use by physicians…
Intraventricular and Intrathecal Therapy
Intraventricular and Intrathecal Therapy Morris D. Groves Arthur D. Forman Victor A. Levin Tumor cells from almost any solid or hematologic malignancy can metastasize and come to rest in the…
