Abstract Inherited bone marrow failure syndromes (IBMFS) are a rare but important consideration in the differential diagnosis of cytopenias in childhood [1]. However, diagnosis of IBMFS in the newborn period…
Abstract Neonates frequently suffer from life threatening infections. Immaturity of the immune system increases the vulnerability to infection, and the preterm and term neonatal immune system has specific deficiencies relative…
Abstract Hematopoiesis refers to the continuous production and release of blood cells into the circulation. As blood cells become old or injured, self-renewing hematopoietic stem cells (HSC) proliferate and differentiate…
Abstract Ancient concepts of the blood were described by Hippocrates and Galen 2000 years ago in their doctrine of “humors.” It was believed that the body was made up of…
