Insulin Resistance and Atherosclerosis

Apr 14, 2017 by in ENDOCRINOLOGY Comments Off on Insulin Resistance and Atherosclerosis

Fig. 3.1 Insulin resistance (IR) is selective to the PI3K (predominantly metabolic) effects of insulin. Hyperinsulinemia, a common concomitant of IR, results in exaggerated MAPK (predominantly nuclear and mitogenic) effects…

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Laboratory Assessment of Lipoproteins in Diabetes

Apr 14, 2017 by in ENDOCRINOLOGY Comments Off on Laboratory Assessment of Lipoproteins in Diabetes

Intercurrent illness (with acute phase inflammation) Increased VLDL (TG), reduced HDL-C, LDL-C Hemoconcentration (dehydration, upright posture, prolonged tourniquet, squeezing to obtain fingerprick sample) Proportionate increase in most analytes, including lipoproteins…

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