Vasculitides
Vasculitides James R. Stone John H. Stone The vasculitides comprise a heterogeneous group of disorders characterized by inflammation that targets and damages blood vessels. Vasculitis may be caused by infection…
The Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndromes
The Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndromes James N. George Thrombotic thrombocytopenic purpura (TTP)1,2 and the hemolytic uremic syndrome (HUS)3,4 were described initially as distinct disorders. Although they may…
Consumptive Thrombohemorrhagic Disorders
Consumptive Thrombohemorrhagic Disorders Marcel Levi Donald I. Feinstein Robert W. Colman Victor J. Marder Known variously as disseminated intravascular coagulation (DIC), defibrination, or the consumption coagulopathies, consumptive thrombohemorrhagic disorders are…
Overview of Complex Thrombohemorrhagic Disorders
Overview of Complex Thrombohemorrhagic Disorders Theodore E. Warkentin Victor J. Marder This overview of “complex thrombohemorrhagic disorders” emphasizes their heterogeneous clinical presentation ranging from bleeding to microvascular and macrovascular thrombosis…
Pathogenesis and Treatment of Biomaterial-Associated Thrombosis
Pathogenesis and Treatment of Biomaterial-Associated Thrombosis Maud B. Gorbet Michael V. Sefton Cardiovascular device manufacturers rely on elegant device designs and systemic pharmacologic agents to work wonders with existing materials…
Unusual Sites of Arterial Occlusion
Unusual Sites of Arterial Occlusion Philip A. Kalra Jon G. Moss Peter Wiedemann UNUSUAL SITES OF ARTERIAL OCCLUSION In this chapter, we consider occlusive arterial diseases as they affect three…
Medical and Surgical Treatment of Peripheral Arterial Disease
Medical and Surgical Treatment of Peripheral Arterial Disease Philip Joseph Saurabh Kalra Sonia Anand Peripheral arterial disease (PAD) affects approximately 27 million individuals in North America and Europe, and its…
Ischemic Stroke: Acute Thrombolytic Therapy, Antithrombotic Approaches, and General Management
Ischemic Stroke: Acute Thrombolytic Therapy, Antithrombotic Approaches, and General Management Gregory J. Del Zoppo Jeffrey L. Saver PREVENTION AND TREATMENT OF ACUTE STROKE Stroke is a syndrome of fixed or…
Prevention of Thromboembolic Stroke in Patients with Atrial Fibrillation, Valvular Heart Disease, or Cardiomyopathy
Prevention of Thromboembolic Stroke in Patients with Atrial Fibrillation, Valvular Heart Disease, or Cardiomyopathy Thomas L. Kawano Jonathan L. Halperin Patients with various forms of cardiac disease are at risk…
Pathophysiology of Thromboembolic Stroke
Pathophysiology of Thromboembolic Stroke Emer R. Mcgrath Martin J. O’Donnell Stroke is defined by the World Health Organization (WHO) as “rapidly developing clinical signs of focal (at times global) disturbance…
