Fig. 10.1 Systemic thromboembolic conditions in children and adults. TTP thrombotic thrombocytopenic purpura, ECMO extracorporeal membrane oxygenation, TAFI thrombin-activatable fibrinolysis inhibitor, TFPI tissue factor pathway inhibitor 10.2 Inherited Thrombophilia and…
Fig. 8.1 Population-based epidemiological study of 7774 patients with ITP in a Japanese population [9]. A population of 7774 patients with ITP were analyzed retrospectively using the database registry of…
Disease Mutated gene Inheritance Associated features 1. Severe congenital neutropenias SCN1 (elastase deficiency) ELANE AD Susceptibility to myelodysplastic syndrome/acute myelogenous leukemia SCN2 (GFI1 deficiency) GFI1 B/T lymphopenia SCN3 (Kostmann disease) HAX1…
