Clinically Nonfunctioning Sellar Masses

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Clinically Nonfunctioning Sellar Masses

FIGURE 16-1. Demonstration of clonality of pituitary adenomas. Southern blots from extracts of gonadotroph adenomas (c lanes) and peripheral leukocytes (d lanes) of five women who were heterozygous for the…

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The Pineal Gland and Melatonin

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on The Pineal Gland and Melatonin

Figure 22-1. Anatomic relationship among the pineal gland, hypothalamus, and pituitary gland. The pineal gland also receives parasympathetic and peptidergic innervation originating in the hypothalamus, mesolimbic system, and visual structures….

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Glucocorticoid Action: Physiology

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Glucocorticoid Action: Physiology

FIGURE 97-1. Outline of regulation and actions of glucocorticoids. See text for details. Normal glucocorticoid levels are regulated in a range and time course that reflect varying physiologic needs as…

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Menopause

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Menopause

FIGURE 135-1. This chart describes a working model of the female reproductive lifespan, including but not limited to the menopausal transition. The final menstrual period (FMP) is indicated at time…

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The Endocrinology of Sexual Behavior and Gender Identity

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on The Endocrinology of Sexual Behavior and Gender Identity

Chapter 124 The Endocrinology of Sexual Behavior and Gender Identity Louis J. Gooren Prenatal, Postnatal, and Childhood Years Sexual Differentiation Brain Sexual Differentiation Disorders of Sexual Differentiation Complete Androgen Insensitivity…

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Glucagon and the Glucagon-Like Peptides

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Glucagon and the Glucagon-Like Peptides

FIGURE 35-1. Structure of proglucagon and the proglucagon-derived peptides. The amino acid sequences of glucagon, glucagon-like peptide (GLP)-1, and GLP-2 are shown, as well as the cleavage site for dipeptidyl…

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Prolactin

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Prolactin

FIGURE 9-1. Biosynthesis of prolactin (PRL). The PRL gene is depicted at the top of the figure as consisting of five exons (black rectangles) encoding the structural gene for preprolactin…

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Control of Hormone Secretion

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Control of Hormone Secretion

FIGURE 3-1. Schematic diagram of the anterograde secretory pathway in a peptide hormone–secreting endocrine cell. Secretory proteins synthesized in the endoplasmic reticulum (ER) are transported to and through Golgi stacks…

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Classification and Diagnosis of Diabetes Mellitus

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Classification and Diagnosis of Diabetes Mellitus

Neonatal diabetes is rare and may be transient or permanent.37 Several genetic defects have been identified in these patients, most notably mutations in the adenosine triphosphate (ATP)-sensitive potassium channel (KATP)…

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Hypothalamic Syndromes

Jan 16, 2017 by in ENDOCRINOLOGY Comments Off on Hypothalamic Syndromes

FIGURE 12-1. Schematic representation of lateral brain section demonstrating hypothalamic nuclei. Dashed lines represent the frontal (coronal) section planes illustrated in Figures 12-2 and 12-3. 1, preoptic nucleus; 2, paraventricular…

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