Age Greater parity Smoking Cardiovascular disease including: Hypertension Patent foramen ovale Metallic heart valve Renal disease Migraine with aura Heritable thrombophilia Acquired thrombophilia: antiphospholipid syndrome Hyperhomocystinemia Hematological disorders Thrombotic microangiopathies…
Heritable thrombophilia Possible heritable component Acquired risk factors for venous thrombosis Antithrombin deficiency High factor VIII/VWF Increasing age (over 35 in pregnancy) Protein C deficiency High factor IX Pregnancy Protein…
Fig. 2.1 Coagulation mechanism and targets for action of different anticoagulants. UFH unfractionated heparin, AT antithrombin, LMWH low-molecular-weight heparin The amount of activated factor X is further enhanced by the…
