Prognostic and Predictive Factors in Breast Cancer: Introduction Print Section Listen Early detection and improvement in adjuvant systemic therapy has resulted in a decrease in breast cancer mortality. However, each…
Male Breast Cancer: Introduction Print Section Listen Males infrequently develop breast cancer; hence the dearth of prospective randomized trials in male breast cancer. Our knowledge of the disease has been…
Precursor and Preinvasive Lesions of the Breast Print Section Listen The multistep model for breast carcinogenesis suggests that invasive carcinomas arise from preinvasive “hyperplastic” and neoplastic proliferations. These early proliferative…
Pathology of the Breast and Clinical Management: Introduction Print Section Listen The purpose of this chapter is to provide general guidelines on specimen evaluation and highlight some clinically relevant issues,…
Prophylactic Mastectomy: Introduction Print Section Listen Patients at increased risk of breast cancer have a range of treatment options available to decrease their risk of breast cancer development. The absolute…
The Value of Quantitative Risk Assessment Print Section Listen There are already several approaches available to increase the chances of diagnosing breast cancer at an early, curable stage, or of…
History, Physical Examination, and Staging: Introduction Print Section Listen Breast cancer is being detected at earlier stages due to improvements in imaging and increased public awareness of the breast health…
Definition of Chemoprevention and Identifying Women at Risk Print Section Listen Breast cancer is a complex disease, resulting from the interaction of nonmodifiable factors such as an individual’s genome, age…
Metastasis: Introduction Print Section Listen Breast cancer remains a leading cause of morbidity and mortality in women,1 mainly due to the propensity of primary breast tumors to metastasize to regional…
Genetic Predisposition Syndromes: Introduction Print Section Listen In 1860, Dr. Broca, a French surgeon, reported on the pedigree of his wife’s family because of her early-onset breast cancer and the…
