ONCOLOGY

Invasive Cancer of the Vagina

Sep 13, 2019 by in ONCOLOGY Comments Off on Invasive Cancer of the Vagina

Outline Squamous Cell Carcinoma of the Vagina Epidemiology Screening Signs and Symptoms Diagnostic Considerations Staging Patterns of Spread Prognostic Features Management Survival and Recurrence Rare Histologies Adenocarcinoma and Clear Cell…

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Gestational Trophoblastic Disease

Sep 13, 2019 by in ONCOLOGY Comments Off on Gestational Trophoblastic Disease

Outline Hydatidiform Mole Epidemiology Cytogenetics and Pathology Presentation and Symptoms Diagnosis Evacuation Risk Factors for Postmolar Gestational Trophoblastic Neoplasia Postmolar Surveillance Prophylactic Chemotherapy After Molar Evacuation Coexistent Molar Pregnancy With…

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Endometrial Hyperplasia, Estrogen Therapy, and the Prevention of Endometrial Cancer

Sep 13, 2019 by in ONCOLOGY Comments Off on Endometrial Hyperplasia, Estrogen Therapy, and the Prevention of Endometrial Cancer

Outline Introduction Clinical Presentation Endometrial Hyperplasia: Pathologic Diagnostic Criteria Management Decisions for Atypical Endometrial Hyperplasia (Endometrial Intraepithelial Neoplasia) Management of Endometrial Hyperplasia Without Atypia Prevention of Endometrial Cancer Benefits and…

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Sarcoma of the Uterus

Sep 13, 2019 by in ONCOLOGY Comments Off on Sarcoma of the Uterus

Outline Classification Incidence and Epidemiology Leiomyosarcoma Clinical Profile Surgical Management Adjuvant Therapy Management of Recurrent Disease Endometrial Stromal Sarcoma Clinical Profile Surgical Management Adjuvant Therapy Management of Recurrent Disease Other…

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Preinvasive Disease of the Cervix

Sep 13, 2019 by in ONCOLOGY Comments Off on Preinvasive Disease of the Cervix

Outline Natural History Epidemiology Human Papillomavirus Vaccination Screening Core Principles for Managing Abnormal Screening Test Results Managing Abnormal Cervical Cancer Screening Test Results Managing Abnormal Results in Young Women Unsatisfactory…

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Preinvasive Disease of the Vagina and Vulva and Related Disorders

Sep 13, 2019 by in ONCOLOGY Comments Off on Preinvasive Disease of the Vagina and Vulva and Related Disorders

Outline Embryology Examination and Treatment of Females Exposed to Diethylstilbestrol Nonneoplastic Epithelial Disorders of the Vulva Lichen Simplex Chronicus Lichen Sclerosus Lichen Planus Diagnosis and Treatment Intraepithelial Neoplasia of the…

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Targeted Systemic Delivery of Therapeutic siRNA

Sep 7, 2019 by in ONCOLOGY Comments Off on Targeted Systemic Delivery of Therapeutic siRNA

Keywords siRNA, RNAi, cancer, targeted delivery, theranostics   Introduction RNA interference (RNAi) is a relatively new and highly promising technology for gene therapy ( Figure 4.1 ). RNAi is a…

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Selectively Replicating Oncolytic Adenoviruses Combined with Chemotherapy, Radiotherapy, or Molecular Targeted Therapy for Treatment of Human Cancers

Sep 7, 2019 by in ONCOLOGY Comments Off on Selectively Replicating Oncolytic Adenoviruses Combined with Chemotherapy, Radiotherapy, or Molecular Targeted Therapy for Treatment of Human Cancers

Keywords Oncolytic virus, adenovirus, chemotherapy, radiotherapy, molecular targeted therapy, clinical trial, combined therapy   Introduction Gene and vector-based molecular therapies for cancer encompass a wide range of treatment types that…

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Modified Oncolytic Herpesviruses for Gene Therapy of Cancer

Sep 7, 2019 by in ONCOLOGY Comments Off on Modified Oncolytic Herpesviruses for Gene Therapy of Cancer

Keywords Herpes simplex virus, immunotherapy, oncolysis, advanced cancer, vaccine   Introduction Recent advances in viral genome sequencing and elucidation of viral protein function combined with a better understanding of tumor…

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Gene Therapy in Radiotherapy of Cancer

Sep 7, 2019 by in ONCOLOGY Comments Off on Gene Therapy in Radiotherapy of Cancer

Keywords Radiotherapy, Radioprotection, MnSOD-PL   Introduction: The Radiotherapy Update Radiation therapy (radiotherapy) remains one of the three critical approaches toward the management of the cancer patient, along with surgery and…

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