Cancer of the skin is the most common human malignancy, and its incidence is rising worldwide. There are approximately 900,000 to 1,200,000 new cases of skin cancer annually in the…

Acute Leukemias Acute leukemias are neoplastic disorders marked by uncontrolled proliferation of hematopoietic cells, with a predominance of immature lymphoid or myeloid cells, in the bone marrow and peripheral blood….

The Central Brain Tumor Registry of the United States (CBTRUS) estimated 51,410 new cases of malignant and nonmalignant brain tumors in 2007. Among children the incidence is 4.5 cases per…

Multiple myeloma and related disorders compose a spectrum of diseases that are characterized by the autonomous proliferation of differentiated lymphoid cells and plasma cells whose physiologic function is to secrete…

Sarcomas Sarcomas are a complex and heterogeneous family of malignancies of mesenchymal origin. As opposed to carcinomas, which represent malignancies of epithelial tissues, sarcomas are neoplastic disorders that differentiate into…

Esophageal Cancers The prevalence of esophageal cancer varies over 20-fold throughout the world. Esophageal cancer is most common in central Asia and remains relatively rare in the United States. Approximately…

The incidence of cancer in childhood is quite rare compared with the incidence in adults; approximately 6500 new cases are diagnosed in the United States each year. Nevertheless, cancer remains…

The acquired immunodeficiency syndrome (AIDS) epidemic is in its third decade, and the number of people infected with the human immunodeficiency virus-1 (HIV) in the United States is approaching 1…

Prostate Cancer Prostate cancer is the most commonly diagnosed noncutaneous malignancy in men in the United States. In 2007, over 218,000 cases will be diagnosed and over 27,000 men will…

Ovarian Carcinoma Though not the most common gynecologic malignancy, epithelial ovarian cancer is the most lethal, affecting approximately 26,000 women per year and causing at least 15,000 deaths in the…