Figure 2.1 Large lateral nasal defect The skin graft was ‘quilted’ in place with a quilting suture through the base of the wound (Fig. 2.2). This method allows me to…
Figure 11.1 Box shows area of application of Aldara for s BCC Histological report is detailed above – which reveals a non-ulcerated tumor of 0.8 mm Breslow thickness, Clark Level…
Fig. 1 The balance of DNA damage and DNA repair determines the stability of a genome It is becoming more and more apparent that the fine tuning of genomic stability is…
Wild-type Aneuploid strains Method Notes Haploid (1n)16 chr Monosomies (n − 1) Centromere silencing (CS) Inviable Disomies (n + 1) CS, Chromosome transfer (CT) and meiois of 3n or 5n (RM) 12 disomes from…
Fig. 1 Numbers of somatic structural variants (SV) and single nucleotide variants (SNVs) identified in prostate (Berger et al. 2011) and colorectal cancer (Bass et al. 2011) Insight into structural genomic…
Fig. 1 Telomere-DNA is an evolutionarily conserved GT-rich repetitive sequence. Basically all eukaryotes use GT-rich repetitive sequences at the ends of their chromosomes (telomeres). Despite considerable variation in telomere length and…
Fig. 1 Karyotype aberrations. Doubling the karyotype results in polyploidy, whereas loss or gain of one entire chromosome results in whole chromosome aneuploidy. Unbalanced structural rearrangements such as gain or loss…
Fig. 1 Schematic illustration of commonly observed numerical and structural chromosome alterations identified in solid tumors, and the methodologies capable of their detection. Detection of an alteration, however, is not necessarily…
Fig. 1 Summary of the major mechanisms causing CIN in human cancer cells. The major defects leading to chromosome missegregation in human cancer cells are a premature loss of sister chromatid…
Fig. 1 a HDAC2 and TXNL1 immunohistochemical detection in colorectal cancer specimens based on a tissue microarray. Image examples are given at 800-fold magnification. b Tissue-microarray-based immunohistochemical evaluation of HDAC2 and…
