Lymphocyte Receptor Pathways
(1) Institut Bergonié, Bordeaux, France Abstract The two types of lymphocytes, B and T, which are, respectively, responsible for humoral and cell-mediated immunity, express membrane receptors in relation to…
ONCOLOGY
Ion Channel-Coupled Receptors
(1) Institut Bergonié, Bordeaux, France Abstract Conduction of nerve impulse is a major signalling pathway in multicellular organisms and requires ion channels situated at the level of plasma membranes…
Semaphorins and Adhesion Molecules
(1) Institut Bergonié, Bordeaux, France Abstract Semaphorins constitute a group of signalling proteins originally described in the central nervous system where they are involved in the growth of the…
Notch Pathway
(1) Institut Bergonié, Bordeaux, France Abstract The Notch pathway, as the Wnt–β-catenin pathway, is an important signalling pathway in vertebrate and invertebrate development. It is involved in embryogenesis and…
Hedgehog Pathway
(1) Institut Bergonié, Bordeaux, France Abstract The Hedgehog pathway is an important signalling pathway for the development of vertebrates and invertebrates. It is involved in embryogenesis and morphogenesis and…
Cytokines Pathway
(1) Institut Bergonié, Bordeaux, France Abstract An important group of signalling molecules operate through a pathway which is slightly different from that described in Chap. 1: their receptors do…
Wnt Pathway
(1) Institut Bergonié, Bordeaux, France Abstract The term Wnt was forged by contraction of Win gless-type mouse mammary tumour virus int egration site after the discovery on a viral…
TGFβ Pathway
(1) Institut Bergonié, Bordeaux, France Abstract Transforming growth factor beta (TGFβ) is the lead of a large family of factors studied in this chapter, which comprise several stricto sensu…
Metabolic Emergencies in Oncology
Metabolic Emergencies in Oncology Ephraim Paul Hochberg INTRODUCTION Metabolic emergencies represent rare events in the care of cancer patients. In contrast to the measured pace of most of oncology, these…
Molecular Targeted Drugs
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