Accurate diagnosis and staging of pancreatic neoplasms is essential for surgical planning and identification of locally advanced and metastatic disease that is incurable by surgery. The ability to position the…
Carcinogenic progression in the pancreas arises through a well-established stepwise accumulation of molecular aberrations from a normal cell to an invasive adenocarcinoma. Recent large-scale sequencing efforts have provided insight into…
Imaging plays a central role in the management of patients with suspected or known periampullary masses, including the initial diagnosis, staging, and follow-up to assess treatment response or recurrence. Use…
Nipun B. Merchant, MD, FACS, Editor These three “rules” of surgical training are facetiously instilled into the psyche of all new surgical residents. The third rule was based on the…
Nicholas J. Petrelli, MD, FACS, Consulting Editor This issue of the Surgical Oncology Clinics of North America is devoted to pancreatic neoplasms. The guest editor is Nipun Merchant, MD. Dr…
Lobectomy is the gold standard treatment in operable patients with surgically resectable non–small cell lung cancer. Thoracoscopic lobectomy has emerged as an option for surgeons facile with the technique. Video-assisted…
Advances in surgical, radiation, and interventional radiology therapies carry a reduction in morbidity associated with therapy. Aggressive management of patients with oligometastatic non–small cell lung cancer offers the potential for…
Targeted therapy and immunotherapy have changed the treatment paradigm of non–small cell lung cancer (NSCLC). Distinct molecular subtypes of NSCLC have been described over the past 20 years, enabling the emergence…
Patients with stage I and stage II non–small cell lung cancer undergoing complete resection have a 40% to 70% 5-year overall survival despite optimal local therapy. Chemotherapy administered after complete…
Locally advanced (stage IIIA) non–small cell lung cancer (NSCLC) is confined to the chest, but requires more than surgery to maximize cure. Therapy given preoperatively is termed neoadjuvant , whereas…
