ONCOLOGY

Gastrointestinal Toxicities of Immunotherapy

Mar 11, 2021 by in ONCOLOGY Comments Off on Gastrointestinal Toxicities of Immunotherapy

Introduction Novel agents have revolutionized the treatment of cancer, resulting in many benefits for patients. These same agents, however, have been associated with new toxicity profiles compared with traditional chemotherapy….

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Endocrine Toxicities of Immunotherapy

Mar 11, 2021 by in ONCOLOGY Comments Off on Endocrine Toxicities of Immunotherapy

Introduction In the past two decades, the field of cancer immunotherapy evolved from a niche specialty to the frontlines of the fight against cancer. Unlike chemotherapy, immunotherapy unleashes the body’s…

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Mechanisms of Immune-Related Adverse Events

Mar 11, 2021 by in ONCOLOGY Comments Off on Mechanisms of Immune-Related Adverse Events

Introduction ■ The origins of immunotherapy can be traced back to the early 1900s when Paul Ehrlich postulated that the host immune system plays a role in the early recognition…

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Cardiovascular Toxicities of Targeted Therapy

Mar 11, 2021 by in ONCOLOGY Comments Off on Cardiovascular Toxicities of Targeted Therapy

Introduction Cardiotoxicity is one of the worrisome side effects of cancer-directed therapy. Cardiac adverse events can range from mild to severe and vary between classes of targeted agents. Some relevant…

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Dermatological Toxicities of Targeted Therapy

Mar 11, 2021 by in ONCOLOGY Comments Off on Dermatological Toxicities of Targeted Therapy

Introduction Targeted therapies are a rapidly expanding group of anticancer drugs, which promise to provide better tolerated and higher efficacy medications compared with conventional systemic chemotherapy. Inhibition of novel pathways…

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Pulmonary Toxicities of Targeted Therapy

Mar 11, 2021 by in ONCOLOGY Comments Off on Pulmonary Toxicities of Targeted Therapy

Introduction Prior to the 1990s, cytotoxic chemotherapy was used uniformly for all malignancies. This resulted in heterogeneous responses even within a specific tumor type. As insight was gained about the…

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Gastrointestinal Toxicities of Targeted Therapy

Mar 11, 2021 by in ONCOLOGY Comments Off on Gastrointestinal Toxicities of Targeted Therapy

Introduction Targeted therapies are a category of drugs that inhibit cancer by interfering with specific molecules involved in the growth, progression, and spread of malignant cells. Targeted therapies act on…

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Cancer Treatment Infusion Reactions

Mar 11, 2021 by in ONCOLOGY Comments Off on Cancer Treatment Infusion Reactions

Introduction Cancer treatments have the potential to cause infusion reactions (IRs). It is important to manage IRs because they may cause treatment disruption and require costly medical interventions. Both cytotoxic…

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Cardiovascular Toxicities of Chemotherapy

Mar 11, 2021 by in ONCOLOGY Comments Off on Cardiovascular Toxicities of Chemotherapy

Introduction Cardiotoxic effects of chemotherapy are challenging in nature, since myocardial tissue possesses limited regenerative capacity, which renders the heart susceptible to transient and permanent side effects of chemotherapy agents….

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