ONCOLOGY

Management of Toxicities of Targeted Therapies

Nov 10, 2019 by in ONCOLOGY Comments Off on Management of Toxicities of Targeted Therapies

Summary of Key Points • Epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), BRAF, C-ros oncogene 1 (ROS1), ret proto-oncogene (RET) tyrosine kinase inhibitors (TKIs), several antiangiogenesis agents, and…

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Treatment of Extensive-Stage Small Cell Lung Cancer

Nov 10, 2019 by in ONCOLOGY Comments Off on Treatment of Extensive-Stage Small Cell Lung Cancer

Summary of Key Points • Performance status is universally recognized as an independent prognostic factor and typically correlates with the extent of tumor burden. • As first-line therapy, platinum agent…

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Immunotherapy and Lung Cancer

Nov 10, 2019 by in ONCOLOGY Comments Off on Immunotherapy and Lung Cancer

Summary of Key Points • Immunotherapy has entered a new era in lung cancer and is rapidly changing the standard of care. • Vaccines as monotherapies have shown marginal efficacy…

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New Targets for Therapy in Lung Cancer

Nov 10, 2019 by in ONCOLOGY Comments Off on New Targets for Therapy in Lung Cancer

Summary of Key Points • Treatment of lung cancer is rapidly evolving. Large cell carcinomas as a group have therapeutically relevant driver mutations in nearly 40% of cases. • Despite…

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Maintenance Chemotherapy for Nonsmall Cell Lung Cancer

Nov 10, 2019 by in ONCOLOGY Comments Off on Maintenance Chemotherapy for Nonsmall Cell Lung Cancer

Summary of Key Points • Maintenance therapy offers the possibility of continued active treatment to delay disease progression and symptom deterioration and, more importantly, improved overall survival of patients with…

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