Hereditary Ovarian Cancer
High-grade serous Low-grade serous High-grade endometrioid Low-grade endometrioid Clear cell Mucinous Unspecified carcinoma No. 1501 70 64 14 58 16 166 BRCA1 (%) 10.3 4.3 6.3 0 6.9 0…
ONCOLOGY
Strategies for the Management of Epithelial Ovarian Cancer
Fig. 8.1 Flowchart of fundamental strategies for the management of epithelial ovarian cancer. Cited from Komiyama et al. [3] with slight modifications 8.2 Surgical Management 8.2.1 Early (Localized to the Ovary)-Staged…
Screening and Prevention of Ovarian Cancer
St Bartholomew’s Hospital trial The Boston study Ref. [9] [10] Published 1996 2003 Design Single arm prospective study Single arm prospective study. Subjects The low-risk asymptomatic women > or = 45 years…
Ovarian Cancer Genome and Molecular Experimental Sciences
Fig. 7.1 HR-deficient and HR-proficient tumors of high-grade serous ovarian carcinoma [8] HR pathway proficient tumors with CCNE1 amplification were common in primary resistant and refractory cases [7]. Inactivation of…
Breast MRI: Standard Terminologies and Reporting
Amount of fibroglandular tissue (FGT) Almost entirely fat Scattered fibroglandular tissue Heterogeneous fibroglandular tissue Extreme fibroglandular tissue Background Parenchymal Enhancement Level Minimal Mild Moderate Marked Symmetric or Asymmetric Focus Masses…
Multiparametric Imaging: Cutting-Edge Sequences and Techniques Including Diffusion-Weighted Imaging, Magnetic Resonance Spectroscopy, and PET/CT or PET/MRI
Fig. 15.1 7 T DCE. Invasive ductal carcinoma G2 in a 50-year-old woman at 1 o’clock in the right breast. (a) At DCE MRI of the breast at 7 T…
MRI and Preoperative Staging in Women Newly Diagnosed with Breast Cancer
TX Primary tumor cannot be assessed T0 No evidence of primary tumor Tis Carcinoma in situ Tis (DCIS) Ductal carcinoma in situ Tis (LCIS) Lobular carcinoma in situ Tis (Paget’s)…
Post-operative Findings/Recurrent Disease
Fig. 8.1 Typical timeline of mammographic (MG) findings following Breast Conservation Therapy Early findings of postoperative collections such as seroma and/or hematoma, breast edema and skin thickening, are most pronounced…
Breast MRI and Implants
Fig. 6.1 (a) Axial STIR with water suppression (silicone sensitive) MRI image showing bilateral intact silicone implants. Signal from the saline component of the phantom (white arrow) is suppressed. High…
MRI Appearance of Invasive Breast Cancer
Fig. 10.1 Axial and sagittal T1 post contrast images demonstrate an irregularly shaped and irregularly marginated mass with heterogeneous enhancement (arrows). Biopsy demonstrated ER/PR + HER-2- IDC 10.3.2 Her2 Enriched…
