Diffuse astrocytic and oligodendroglial tumors ICD-O codes Diffuse astrocytoma, IDH-mutant 9400/3 Gemistocytic astrocytoma, IDH-mutant 9411/3 Diffuse astrocytoma, IDH-wildtype 9400/3 Diffuse astrocytoma, NOS 9400/3 Anaplastic astrocytoma, IDH-mutant 9401/3 Anaplastic astrocytoma, IDH-wildtype…
Fig. 34.1 Tumor overlap map overlaid on a standard Montreal National Institute (MNI) T1 for all 198 patients, presented according to the neurological convention (left to left and right to…
Fig. 22.1 Proposal of a hodotopical model of functional connectivity in the human brain, with incorporation of anatomical constraints. This networking model was elaborated on the basis of structural-functional correlations…
Fig. 19.1 Motor fMRI. A low grade glioma was located in the right superior frontal gyrus, anteriorly to the precentral sulcus. Presurgical fMRI shows primary sensorimotor activation of the left…
Fig. 3.1 Low-grade glioma classification algorithm according to new WHO guidelines [1] 3.2.2 Integrative Molecular Classification In additional efforts to construct clinically-relevant and objective tumor subclasses, two recent landmark studies…
Fig. 4.1 (a) This infiltrating astrocytoma has hyperchromatic elongated astrocytic nuclei as often seen in the prototypic infiltrating astrocytomas but a significant proportion of tumor cells exhibit abundant globose eosinophilic…
Fig. 11.1 MRI of a patient with an oligodendroglioma WHO grade II in the right frontal pole. A right frontal lobectomy was performed with en-bloc removal of the tumor. Postoperative…
Fig. 33.1 Axial FLAIR-weighted MRI showing a typical illustration of a “false DLGG”, which is in fact a highly diffuse glioblastoma. In its initial phase of low density (left), such…
© Springer-Verlag London Ltd. 2017Hugues Duffau (ed.)Diffuse Low-Grade Gliomas in Adults10.1007/978-3-319-55466-2_29 29. Emerging Therapies for Diffuse Low Grade Glioma James Wright1 and Andrew Edward Sloan1, 2, 3 (1) Department of Neurological Surgery, University Hospitals-Cleveland Medical Center and…
Fig. 28.1 Personalized dynamic multimodal therapeutic strategy in DLGG, with the goal to prevent malignant transformation while preserving quality of life 28.2.1 The Multistage Surgical Attitude As extensively demonstrated in…
