Highlights • All of Us is a prospective clinic genomic database with a diverse population. • Black, Hispanic, and Asian men are less likely to be screened for prostate cancer….

Highlights • Renal Cell Carcinoma (RCC) as high number cases in western countries. • 3D reconstructions of kidneys and tumors are useful for the surgical operations. • Contact Surface Area…

Highlights • Regarding the controversy over the prognostic value of the primary tumor, our study supports that the level of IVCTT and tumor size have no significant prognostic value. •…

Highlights • Combination systemic therapies (STs) including immuno-oncologic (IO) and VEGF-inhibiting (VEGFi) agents, predominantly tyrosine kinase inhibitors (TKI), have become the standard of care for metastatic clear cell carcinoma. •…

Highlights • Intravesical chemotherapy significantly reduces intravesical recurrence risk after NUT at 12 (OR 0.46) and 24 months (OR 0.41). • No statistically significant difference was found between single intra…

Highlights • Interrater agreement for both the 2019 and 2005 Bosniak classifications was comparable, showing fair to moderate agreement among resident raters. • The Bosniak 2019 version has increased the…

Highlights • Identified 12 gut microbial taxa potentially linked to prostate cancer risk using MR analysis. • Employed robust statistical methods to ensure reliability of causal inference results. • Explored…

Highlights • Real-world study of US adults with la/mUC receiving first-line therapy. • Most received platinum-based chemotherapy (48.2%) or PD-1/L1 inhibitor (35.5%). • All first-line therapies had short survival, high…

Highlights • In preclinical studies, it has been demonstrated that antihistamines may reverse macrophage immunosuppression, reactivate t-cell cytotoxicity, and enhance the immunotherapy response. • By use of individual patient data…