Chapter 72 Lipid Disorders Peter Reiss, MD, PhD, Marc van der Valk, MD, PhD INTRODUCTION The use of highly active antiretroviral therapy (HAART)1–3 is frequently associated with side effects. Among…

Chapter 35 Managing Pregnant Patients James McIntyre, FRCOG INTRODUCTION The AIDS epidemic continues to affect many millions of people globally. UNAIDS estimated that there were 39.5 million people living with…

Chapter 33 Acute HIV Infection Saurabh Mehandru, MD, Martin Markowitz, MD INTRODUCTION Acute infection with the human immunodeficiency virus type 1 (HIV-1) is a unique stage of the virus–host interaction….

Chapter 67 Hematologic Disease Richard D. Moore, MD Hematologic abnormalities are widely recognized and are of significant clinical importance in the management of patients with human immunodeficiency virus (HIV) infection….

Chapter 82 HIV/AIDS-Related Internet Resources Richard A. Colvin, MD, PhD INTRODUCTION The Internet and proliferation of the personal computer allowed information to be shared among scientists, clinicians, and patients at…

Chapter 56 Sexually Transmitted Human Papillomavirus Infection William Bonnez, MD Human papillomaviruses (HPVs) represent a large group of viruses that infect mostly the squamous epithelia of the body. They cause…

Chapter 80 AIDS-Related Medications Alice K. Pau, PharmD, Sarah Robertson, PharmD INDEX OF MEDICATIONS Antiretrovirals 1408 Abacavir 1408 Amprenavir 1409 Atazanavir 1409 Darunavir 1410 Delavirdine 1410 Didanosine 1410 Efavirenz 1411…

Chapter 8 Stavudine Andrew T. Pavia, MD STRUCTURE Stavudine (2′,3′didehydro-2′,3′-didoxythymidine: d4T), like zidovudine, is an analog of thymidine (Fig. 8-1). It differs from thymidine by replacement of the hydroxyl group…

Chapter 51 Epstein–Barr Virus and Kaposi Sarcoma-Associated Herpesvirus Eric Johannsen, MD Epstein–Barr virus (EBV), the agent of infectious mononucleosis, is associated with the HIV-related syndromes of oral hairy leukoplakia (OHL)…

Chapter 57 JC Virus Neurologic Infection Sunil Chauhan, MD, MsPH, Colin D. Hall, MBChB Progressive multifocal leukoencephalopathy (PML) was initially described by Astrom and colleagues in 1958,1 as a complication…