Coagulation Testing and Transfusion Medicine
Fibrinogen deficient curve % Activity Fibrinogen, mg/dL PT (s) (normal 10.7–15.0 s) PTT (s) (normal 25–40 s) 100 288 11 28 80 230.4 11.4 29.8 70 201.6 11.6 29.8 40…
HEMATOLOGY
Pharmacogenetic Testing for Anticoagulant and Antiplatelet Therapies
CYP2C9 VKORC1 *1/*1 *1/*2 *1/*3 *2/*2 *2/*3 *3/*3 GG Typical Typical Moderate ↓ Moderate ↓ Moderate ↓ Significant ↓ AG Typical Moderate ↓ Moderate ↓ Moderate ↓ Significant ↓ Significant…
Collection of Coagulation Specimens
Hematocrit, % Blood volume (excluding citrate), mL 4.5 2.7 1.8 0.9 56 0.41 0.24 0.16 0.08 57 0.40 0.24 0.16 0.08 58 0.39 0.23 0.16 0.08 59 0.38 0.23 0.15…
Acquired Coagulation Disorders and TTP
Fig. 8.1 Generation of cross-linked fibrin by thrombin and factor XIIIa following activation of coagulation, and consequences of plasmin degradation of cross-linked fibrin. (a) Following activation of coagulation, thrombin activates…
Testing for Acquired Platelet Disorders
8. Kunz D, Kunz WS, Scott CS, et al. Automated CD61 immunoplatelet analysis of thrombocytopenic samples. Br J Haematol. 2001;112:584–92.PubMedCrossRef 9. De la Salle BJ, McTaggart PN, Briggs C, et…
Role and Responsibilities of the Laboratory Director
General responsibilities Personnel Facilities and safety Test procedures Quality management Consultation and education Communication Operational management Overall operation and administration Needs assessment Biosafety Test menu selection Quality program Accessible to…
Instrumentation for the Coagulation Laboratory
Manufacturer Instrument Clot detection method Compensation for interfering substances Instrumentation laboratories ACL series Photo-optical Interrogating wavelength Siemens healthcare diagnostics Sysmex series Photo-optical Blank measurement BCS Photo-optical Blank measurement Second wavelength…
Treatment of Pseudomyxoma Peritonei from Non-appendiceal Primary Sites
Fig. 3.1 CT scan in a patient with urachal cancer through the upper abdomen showing large volume disease in the right upper quadrant, left upper quadrant, and lesser omentum (From…
Benign Types of Peritoneal Mesothelioma
Type of benign mesothelioma Characteristics Benign multicystic mesothelioma Well-differentiated papillary mesothelioma Benign adenomatoid type of mesothelioma Predilection Young to middle-aged women Reproductive age women Reproductive age women and men Predisposing…
Peritoneal Metastasis from Small Bowel Adenocarcinoma Associated with Crohn’s Disease
Crohn’s related risk factors for small bowel adenocarcinoma Long duration of CD Area of CD inflammation Jejunal CD Strictures Fistula Bypassed segment CD medications Young age Male gender Tobacco-alcohol-diet The…
