C-Terminal Fragment of Adiponectin Receptor Clinical Correlations
Specimen type Patient group – Ig CTF ng/mL n Aver sd min max Serum Normal 25 322.5 173.4 55.5 778.8 Serum Liver disease 23 1141.2 1514.3 293.8 6854.7 Serum Breast…
ENDOCRINOLOGY
Cardiovascular and Metabolic Syndrome Impact on Uristatin
Parameter Control group Affect group P-value, affected vs. controla,f All Male Female All Male Female All Male Female – n = 133 n = 54 n = 79 n = 55 n = 25 n = 30 – – – – (n,…
Ambiguous Genitalia
Fig. 19.1 Hormonal control of sexual differentiation By 7 weeks of pregnancy a fetus has a dual system—Wolffian ducts with the potential for the development of a male and Müllerian…
Hypoglycemia in the Nondiabetic Patient
Fig. 33.1 Decision tree for the diagnosis and workup of hypoglycemic disorders Seventy-Two Hour Fast The 72-h fast is prolonged withholding of food and caloric fluids until Whipple’s triad has…
Classification and Laboratory Diagnosis of Diabetes Mellitus
Normal Prediabetes Diabetes Insulin not needed Insulin needed for control Insulin needed for survival Type 1 DM Type 2 DM Other specific types Gestational DM Reproduced…
Hirsutism and Virilization
Age Adrenals Ovaries Others Prenatal/neonatal 46,XX CCAH: Maternal androgenizing tumors Maternal drugs Prepubertal 46,XX NCCAH Adrenal adenomas Adrenal carcinomas Adrenal hyperplasia 11β-HSD1 deficiency Androgen producing tumors (sex cord stromal; gonadoblastoma) …
Primary Hyperparathyroidism
Multiple endocrine neoplasia type 1 (MEN 1) Multiple endocrine neoplasia type 2 (MEN 2) Familial hypocalciuric hypercalcemia Familial hypercalciuric hypercalcemia Hyperparathyroidism—jaw tumor syndrome Familial isolated hyperparathyroidism Adapted from ref. [5]…
Metabolic Bone Diseases Other than Osteoporosis
Osteogenesis imperfecta symptoms Atypical fractures Short stature Scoliosis Blue sclera Hearing loss Dentinogenesis imperfecta Laxity of the ligaments Wormian bones Laxity of the skin The types of OI can be…
Idiopathic Short Stature: Diagnostic and Therapeutic Approach
Primary short stature—Skeletal abnormalities With recognizable skeletal dysplasia (achondroplasia, hypochondroplasia) Without recognizable skeletal dysplasia (Turner syndrome, SHOX gene haploinsufficiency) Secondary short stature Malnutrition Psychosocial deprivation Chronic diseases Renal (renal failure,…
Gestational Diabetes
Fig. 28.1 The Pedersen Hypothesis. “Maternal hyperglycemia begets foetal macrosomia” Modified by Freinkel to include nutrients other than glucose (lipids and amino acids) Prior diagnostic pathways and nomenclature for diagnosis…
