Tumor involvement of the trigone and urethra at the time of robot-assisted radical cystectomy is associated with adverse oncological outcomes

May 11, 2025 by in ONCOLOGY Comments Off on Tumor involvement of the trigone and urethra at the time of robot-assisted radical cystectomy is associated with adverse oncological outcomes

Highlights • Residual tumor involvement in the trigone and urethra after radical cystectomy is associated with a higher tumor stage, and positive margins. • It was significantly associated with tumor…

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State of the Art: The Microbiome in Bladder Cancer

May 11, 2025 by in ONCOLOGY Comments Off on State of the Art: The Microbiome in Bladder Cancer

Abstract This review assesses the current understanding of the relationship between the human microbiome and BCa. Recognizing how the microbiome affects the tumor microenvironment provides valuable insights into cancer biology,…

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Organ preservation and oncological efficacy of peniscopically controlled CO 2laser excision of penile squamous cell carcinoma: Early and late results in a high-volume center

May 11, 2025 by in ONCOLOGY Comments Off on Organ preservation and oncological efficacy of peniscopically controlled CO 2laser excision of penile squamous cell carcinoma: Early and late results in a high-volume center

Abstract Objectives To evaluate safety and early and long-term efficacy of CO 2 laser conservative treatments for nonulcerative squamous cell carcinoma (SCC) of the penis. Material and Methods Within our…

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Locations of metastases in and oncological outcomes of patients with metastatic castration-sensitive prostate cancer: Real-world data from a multicenter study

May 11, 2025 by in ONCOLOGY Comments Off on Locations of metastases in and oncological outcomes of patients with metastatic castration-sensitive prostate cancer: Real-world data from a multicenter study

Highlights • Lung-only metastases in mCSPC patients showed better outcomes than other visceral metastases. • Bone metastasis volume significantly influenced CRPC-free survival, unlike lung metastases. • Prognoses for patients with…

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A retrospective analysis of tissue, liquid, and germline testing in Hispanic and non-Hispanic men with advanced hormone-sensitive prostate cancer

May 11, 2025 by in ONCOLOGY Comments Off on A retrospective analysis of tissue, liquid, and germline testing in Hispanic and non-Hispanic men with advanced hormone-sensitive prostate cancer

Highlights • Less than 1% of cancer genome-wide association studies include Hispanic Americans. • Hispanic American men present higher rates of advanced-stage PCa and metastases. • TMPRSS2-ERG (36%) and TMB-High…

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Pathologic prostate cancer grade concordance among high-resolution micro-ultrasound, systematic transrectal ultrasound and MRI fusion biopsy

May 11, 2025 by in ONCOLOGY Comments Off on Pathologic prostate cancer grade concordance among high-resolution micro-ultrasound, systematic transrectal ultrasound and MRI fusion biopsy

Highlights • For image guided prostate bipsy, MRI-microUS and MRI-TRUS fusion biopsy techniques were associated with similar rates of GG upgrade on final pathology after radical prostatectomy. • Both techniques…

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