Edematous Reactions
Edematous Reactions Jared Seth Kahn David X. Gao Sandhya Deverapalli Edema occurs when there is a pathologic accumulation of fluid in either the interstitial spaces or an intracellular compartment. Various…
Erythroderma
Erythroderma Michelle S. Lee Vinod E. Nambudiri Erythroderma is typically defined as diffuse redness affecting over 80% to 90% of the body’s surface area (Figure 11.1). It is a reaction…
Purpuric Reactions
Purpuric Reactions Jasmine Rana Bernice Y. Kwong Purpura is due to red blood cells extravasating into the skin or mucous membranes. Purpuric lesions present as deep red to purple in…
Panniculitis-Like Reactions
Panniculitis-Like Reactions Amanda J. Shelley Katherine A. McDonald Anna Kristine Dewan Panniculitis is an uncommon reaction that may occur secondary to cytotoxic chemotherapy, immune checkpoint inhibitors, or small molecule inhibitors….
Bullous Reactions
Bullous Reactions Rohit Gupta Anisha B. Patel Bullous reactions represent a group of skin toxicities characterized by fluid-filled vesicles or bullae with varying localized or diffuse presentations depending on the…
Intertriginous Reactions
Intertriginous Reactions Rachel Reingold Alina Markova An intertriginous reaction pattern may present as erythematous, desquamative, scaly, dusky or eroded patches or plaques commonly affecting one or more folds in the…
Acneiform Reactions
Acneiform Reactions Michelle S. Lee Vinod E. Nambudiri Acneiform eruptions are a relatively common skin toxicity, occurring across several drug classes, and are observed in up to 80% of patients…
Psoriasiform Reactions
Psoriasiform Reactions Jordan Taylor Said Jennifer T. Huang Psoriasiform reactions are a specific subset of papulosquamous skin toxicities, thought to be induced by chemotherapy agents that impact keratinocyte proliferation, differentiation,…
Morbilliform Reactions
Morbilliform Reactions Connie R. Shi Steven T. Chen Morbilliform eruptions, or exanthematous eruptions, present with numerous erythematous, blanching, nonscaly 3 to 4-mm papules that can coalesce into larger plaques most…
Reactions in Patients with Skin of Color
Reactions in Patients with Skin of Color Oyetewa Oyerinde Michelle S. Lee Jennifer Y. Lin As is the case for the full spectrum of dermatologic disease, manifestations of cutaneous toxicity…
