Platelets, Plasma, and Specialized Coagulation Concentrate Therapies Thomas S. Kickler The biggest driving force in improving the safety of transfusion therapy in bleeding disorders has been the concern by patients…
Therapy with Antifibrinolytic Agents Daphne B. Stewart Victor J. Marder After hemostasis is established in an injured vessel, a highly orchestrated process follows to heal the vessel and to reestablish…
Management of Acute Hemorrhage Micah J. Mooberry Rommel P. Lu Nigel S. Key Evaluation and management of the acutely bleeding patient is a common encounter for the hematologist and is…
Overview of Therapy of Bleeding Disorders Gilbert C. White II Sam Schulman Victor J. Marder Historically, once it was recognized that blood clotting factors were components of plasma, the notion…
Retinopathy Jing Chen Andreas Stahl Lois E. H. Smith The eye is one of the most important sensory organs that enables us to perceive the environment to ensure species survival….
Intracranial Hemorrhage and Subarachnoid Hemorrhage Timolaos Rizos Thorsten Steiner INTRACEREBRAL HEMORRHAGE Epidemiology, Risk Factors and Prognosis Intracerebral hemorrhage (ICH) is an extravasation of blood into the brain parenchyma. Hemorrhagic stroke…
Aneurysms (Large and Small Arteries) Carlos E. Sanchez Sangita Kapur Neal L. Weintraub Aneurysms of the aorta and its branch vessels are a major health care concern; more than 15,000…
Arteriovenous Malformations and Hemangiomas and Cerebral Cavernous Malformations Kevin J. Whitehead Douglas A. Marchuk Mark L. Kahn The cardiovascular system is organized into a hierarchical, branching arrangement by which blood…
Hereditary Hemorrhagic Telangiectasia Michelle Letarte Claire L. Shovlin Hereditary hemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome, was first recognized as a genetic disorder in the 19th century. HHT is…
Disorders of Connective Tissue and Extracellular Matrix Fransiska Malfait Anne De Paepe THE CONNECTIVE TISSUE AND THE EXTRACELLULAR MATRIX The connective tissue is the most abundant tissue throughout the body…
