Adjuvant Systemic Therapy: Bone-Targeted Treatments Robert E. Coleman Bone is the most common site for distant recurrence in breast cancer and is the first location for recurrence in about one-third…
Adjuvant and Preoperative Systemic Therapy for HER2-Positive Breast Cancer Ian E. Krop Eric P. Winer INTRODUCTION HER2/neu is a member of the ErbB family of transmembrane tyrosine kinases. The family…
Adjuvant Chemo Endocrine Therapy Vered Stearns Nancy E. Davidson INTRODUCTION Adjuvant systemic therapy is associated with significant improvements in disease-free and overall survival benefits and is recommended to most women…
Adjuvant Systemic Chemotherapy in Early Breast Cancer Chau Dang Clifford A. Hudis INTRODUCTION In women, breast cancer is the most common life-threatening malignancy, but the second leading cause of cancer…
Lymphedema Sarah A. McLaughlin Breast cancer-related lymphedema remains a feared complication following breast cancer treatment (1) because it is a chronic process that cannot reliably be prevented. Dramatic modifications to…
Adjuvant Systemic Therapy: Endocrine Therapy Mothaffar F. Rimawi C. Kent Osborne INTRODUCTION TO ADJUVANT ENDOCRINE THERAPY Breast cancer causes death because of metastases in distant sites that gradually grow and…
Postmastectomy Radiation Therapy Atif Khan Bruce G. Haffty INTRODUCTION The use of postmastectomy radiation therapy (PMRT) is perhaps one of the most intensively studied topics in oncology and yet continues…
Local Management of the Axilla Monica Morrow Jay R. Harris MANAGEMENT SUMMARY: AXILLA The management of the axillary lymph nodes changed dramatically with the introduction of sentinel lymph node biopsy…
Preserving and Restoring Function after Local Treatment Andrea L. Cheville INTRODUCTION Primary breast cancer treatment is associated with long-term musculoskeletal problems in up to one third of patients. This is…
Axillary Dissection Hiram S. Cody III George Plitas INTRODUCTION For patients with operable breast cancer, axillary node status remains the single most important prognostic factor. The primary goal of axillary…
