DIFFUSE SCLEROSING PAPILLARY THYROID CANCER Part of “CHAPTER 41 – UNUSUAL THYROID CANCERS“ Although initially described in 1953,35 the diffuse sclerosing variant of papillary cancer was first formally defined in…
COLUMNAR CELL VARIANT OF PAPILLARY CARCINOMA Part of “CHAPTER 41 – UNUSUAL THYROID CANCERS“ Columnar cell variant is similar to TCV in that it appears to be a dedifferentiated subtype…
TALL CELL VARIANT OF PAPILLARY CARCINOMA Part of “CHAPTER 41 – UNUSUAL THYROID CANCERS“ The tall cell variant of papillary cancer (TCV) was first identified in a subgroup of papillary…
POORLY DIFFERENTIATED (“INSULAR”) CARCINOMA Part of “CHAPTER 41 – UNUSUAL THYROID CANCERS“ Insular thyroid carcinoma was originally described as Wuchernde Struma20 and later became known as insular carcinoma because of…
ANAPLASTIC THYROID CARCINOMA Part of “CHAPTER 41 – UNUSUAL THYROID CANCERS“ Anaplastic cancer is a rare, aggressive malignancy with mean survival rates of <1 year. These tumors are comprised of…
UNUSUAL THYROID CANCERS Matthew D. Ringel Approximately 10% of thyroid cancers are either poorly differentiated epithelial tumors or nonepithelial malignancies that are included in the World Health Organization (WHO) classification…
MEDULLARY THYROID CARCINOMA Part of “CHAPTER 40 – THYROID CANCER“ Medullary thyroid carcinoma (MTC), first recognized in 1959, is a pleomorphic neoplasm with amyloid struma that arises from the calcitonin-secreting…
FOLLICULAR THYROID CARCINOMA Part of “CHAPTER 40 – THYROID CANCER“ PREVALENCE Follicular thyroid carcinoma accounts for ˜5% to 10% of all thyroid cancers in the United States.11 It occurs at…
PAPILLARY THYROID CARCINOMA Part of “CHAPTER 40 – THYROID CANCER“ PREVALENCE Thyroid carcinoma is classified into four major types, which in decreasing order of frequency are papillary, follicular, medullary, and…
RADIATION AND THYROID CARCINOMA Part of “CHAPTER 40 – THYROID CANCER“ Thyroid carcinoma may be caused by exposure to ionizing radiation. It was the first solid tumor found to have…
