Rhabdomyosarcoma
Rhabdomyosarcoma Leonard H. Wexler Stephen X. Skapek Lee J. Helman A malignant tumor of mesenchymal cell origin is called a sarcoma. Mesenchymal cells normally mature into skeletal muscle, smooth muscle,…
Neuroblastoma
Neuroblastoma Garrett M. Brodeur Michael D. Hogarty Rochelle Bagatell Yael P. Mossé John M. Maris INTRODUCTION Few tumors have engendered as much fascination and frustration for clinicians and researchers as…
Renal Tumors
Renal Tumors Conrad V. Fernandez James I. Geller Peter F. Ehrlich Ashley D. Hill John A. Kalapurakal Jeffrey S. Dome INTRODUCTION The kidney is the site of approximately 7% of…
Liver Tumors
Liver Tumors Rebecka L. Meyers Angela D. Trobaugh-Lotrario Marcio H. Malogolowkin Howard M. Katzenstein Dolores H. López-Terrada Milton J. Finegold HISTORICAL CONTEXT Benign and malignant liver tumors in children are…
Retinoblastoma
Retinoblastoma Richard L. Hurwitz Carol L. Shields Jerry A. Shields Patricia Chévez-Barrios Dan S. Gombos Mary Y. Hurwitz Murali M. Chintagumpala INTRODUCTION Retinoblastoma, a malignant tumor of the embryonic neural…
Embryonal and Pineal Region Tumors
Embryonal and Pineal Region Tumors Murali M. Chintagumpala Arnold Paulino Ashok Panigrahy Cynthia Hawkins Andrew Jae Williams D. Parsons EMBRYONAL TUMORS Embryonal tumors constitute approximately 25% of all primary central…
Gliomas, Ependymomas, and Other Nonembryonal Tumors of the Central Nervous System
Gliomas, Ependymomas, and Other Nonembryonal Tumors of the Central Nervous System Williams D. Parsons Ian F. Pollack Daphne A. Hass-Kogan Tina Y. Poussaint Adekunle M. Adesina Murali M. Chintagumpala Tumors…
Histiocytic Diseases
Histiocytic Diseases Kenneth L. McClain Carl E. Allen John M. Hicks INTRODUCTION Histiocytic disorders are a group of diseases that are characterized by abnormal differentiation or function of “histiocytes.” Although…
Lymphoproliferative Disorders and Malignancies Related to Immunodeficiencies
Lymphoproliferative Disorders and Malignancies Related to Immunodeficiencies Robert J. Hayashi Birte Wistinghausen Bruce Shiramizu INTRODUCTION In 1959, Thomas conceptualized that the immune system played a role in oncogenesis. He hypothesized…
Malignant Non-Hodgkin Lymphomas in Children
Malignant Non-Hodgkin Lymphomas in Children Carl E. Allen Kala Y. Kamdar Catherine M. Bollard Thomas G. Gross INTRODUCTION Non-Hodgkin lymphoma (NHL) of childhood is a diverse collection of different lymphomas…
