Chemical Modifiers of Radiation Response David S. Yoo and David M. Brizel Chemical agents have been administered in conjunction with radiotherapy (RT) for both the enhancement of antitumor therapeutic efficacy…
Stereotactic Radiosurgery and Radiotherapy John C. Flickinger and Ajay Niranjan Stereotactic radiosurgery and radiotherapy are techniques to administer precisely directed, high-dose irradiation that tightly conforms to an intracranial target to…
Methodology of Clinical Trials Yaacov Richard Lawrence, James J. Dignam, and Maria Werner-Wasik In this chapter, we discuss the design, conduct, and analysis of oncology clinical trials, pointing out particular…
Stereotactic Irradiation of Tumors Outside the Central Nervous System Brian D. Kavanagh, Jeffrey D. Bradley, and Robert D. Timmerman Departing from the established traditions of conventionally fractionated external beam radiotherapy,…
Smart Radiotherapy C. Norman Coleman, Eric J. Bernhard, Jacek Capala, Bhadrasain Vikram, and James A. Deye When assigned this chapter title, “Smart Radiotherapy,” we were challenged as to the best…
Intraoperative Radiotherapy Timothy J. Kinsella Intraoperative radiotherapy (IORT) involves the delivery of radiation during surgery using various types of radiation sources/technologies, including intraoperative electron radiation therapy (IOERT), high-dose-rate brachytherapy (HDR-IORT),…
Total-Body and Hemibody Irradiation Kenneth B. Roberts, Zhe Chen, and Stuart Seropian Historically, total-body irradiation (TBI) has been used without stem cell support for palliation of radiation-sensitive disease such as…
We are grateful for the scholarly, meticulous, and thorough work of the contributors to this volume. Through six editions, this book has become the “book of record” for the specialty…
