Chapter 29 Pharmacogenetics of Antiretroviral Agents Catia Marzolini, PharmD, PhD, Richard Kim, MD, Amalio Telenti, MD, PhD INTRODUCTION Pharmacogenomics is an emerging clinical discipline that explores the interaction of drugs…
Chapter 52 Human Herpesvirus-6 and Herpesvirus-7 Infections David W. Kimberlin, MD, John W. Gnann, Jr, MD In 1986 a novel virus was isolated from six patients with lymphoproliferative syndromes, two…
Chapter 13 Nevirapine Marianne Harris, MD, CCFP, Carlos Zala, MD, Robert Hogg, PhD, Julio S.G. Montaner, MD Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. It inhibits…
Chapter 28 HIV Resistance Testing in Clinical Practice Charles A.B. Boucher, MD, PhD, Andrew R. Zolopa, MD, Richard T. D’Aquila, MD INTRODUCTION During the last decade our understanding of both…
Chapter 42 Bartonellosis Jane E. Koehler, MD BARTONELLA INFECTIONS Clinical Presentation The spectrum of disease caused by Bartonella species includes cat scratch disease (B. henselae), bacillary angiomatosis (B. henselae and…
Chapter 27 Integrase Inhibitors and Other New Drugs in Development John J.W. Fangman, MD, Martin S. Hirsch, MD INTRODUCTION Since the second edition of AIDS Therapy in 2003, substantial advances…
Chapter 10 Emtricitabine Michael J. Mugavero, MD, MHS, Melissa F. Wellons, MD, MHS Emtricitabine is a pyrimidine analog with antiviral activity against human immunodeficiency virus (HIV) and hepatitis-B virus (HBV)…
Chapter 2 Primary Care in Developed Countries David H. Spach, MD, Kenneth H. Mayer, MD In developed countries, persons infected with human immunodeficiency virus (HIV) have experienced a profound improvement…
Chapter 7 Zalcitabine John A. Bartlett, MD Zalcitabine (2′,3′-dideoxycytidine, ddC, HIVID) is a pyrimidine analog whose synthesis was originally described by Horwitz et al in 1966.1 The antiretroviral activity of…
