Figure 21.22.1 MAPit overview for mapping m5CG and chromatin accessibility in mammalian nuclei. Nuclei are isolated from cultured cells of interest grown under desired experimental conditions. Isolated nuclei are then…
Related posts: Variation in Humans locus in cancer and aging Single-Molecule Mapping of Protein-DNA Interactions and DNA Methylation by MAPit PCR High-Throughput Arrays for Relative Methylation (CHARM) Methylation Alterations in…
FIGURE 1 | The INK4-ARF signaling network. Physiologic mitogenic signals (green light, top left) stimulate the transcription of genes encoding D-type cyclins and facilitate their assembly into stable complexes with…
Related posts: locus in cancer and aging and Epigenetic Heterogeneity in Cancer Single-Molecule Mapping of Protein-DNA Interactions and DNA Methylation by MAPit PCR High-Throughput Arrays for Relative Methylation (CHARM) Methylation…
Chapter 11Reconstruction New Breasts after Mastectomy RECONSTRUCTION AFTER MASTECTOMY replaces the volume and shape of your breasts. In the hands of a gifted plastic surgeon, reconstruction isn’t just an operation,…
Chapter 10Mastectomy for Risk Reduction and Treatment MASTECTOMY (surgically removing the breasts) is sometimes the wisest course of treatment. Unilateral mastectomy removes one breast; bilateral mastectomy removes both. Although aggressive…
Chapter 17How BRCA Affects Men LIKE WOMEN, MEN CAN INHERIT BRCA MUTATIONS from either parent. And when they do, like women, they face an increased lifetime risk of certain cancers…
Chapter 19Putting the Pieces Together to Make Difficult Decisions You climb a mountain, edging slowly upwards. Rock by rock, step by step, one at a time. From one point to…
Chapter 12Oophorectomy and Other Risk-Reducing Gynecologic Surgeries IF YOU DEVELOP OVARIAN CANCER, your treatment will involve oophorectomy, surgery to remove your ovaries. If you have a BRCA mutation, the most…
Chapter 18Diagnosis Hereditary Cancer JUST TWO GENERATIONS AGO, cancers were rarely discovered until they were well advanced, almost always with dismal outcome. There is still much we don’t know, but…
