Cushing’s syndrome signs and symptoms Common symptoms Physical exam signs Less common symptoms Physical exam signs – Weight gain – Dorso cervical (Buffalo) hump – Supra clavicular fat – Central…
© Springer Science+Business Media New York 2015Terry F. Davies (ed.)A Case-Based Guide to Clinical Endocrinology10.1007/978-1-4939-2059-4_11 11. Treatment of Hypothyroidism: Utility of Adding T3 (Liothyronine) Joy Tsai1 and Nikolaos Stathatos1 (1) Thyroid Unit, Massachusetts General Hospital, Harvard…
June 2008 April 2010 June 2010 August 2010, LT4 1.0 μg/kg bw/day December 2010, LT4 1.4 μg/kg bw/day PRL, ng/ml (n.v. 3–20) 31 Basal: 41 +60’: 34 PRL recovery…
Fig. 2.1 Contrast-enhanced T1-weighted coronal and sagittal MR images; preoperative and 3 months postoperative Why Does Acromegaly Fail to Be Diagnosed for Years? Growth hormone (GH) is the most abundant…
Organ system Manifestations Cardiovascular Bradycardia, heart failure, pericardial effusion CNS Depression, fatigue, cognitive dysfunction, myxedema coma Hematopoietic Macrocytic anemia, target cells Metabolic Hyperlipidemia, weight gain Musculoskeletal Arthralgias, myositis Gastrointestinal Constipation…
Intentional Inadvertent 1. Iatrogenic (a) Suppressive thyroxine dose in thyroid cancer (b) Excessive thyroxine dose to shrink goiter (c) Patient’s insistence on higher thyroid hormone dose 2. Factitious (a) Surreptitious ingestion of thyroid hormone to feign…
Fig. 1.1 Adapted from Neurosurg Focus 29(4):E15, Fleseriu, M., Delashaw, J.B., and Cook, D.M. Acromegaly: a review of current medical therapy and new drugs on the horizon, page 3, Copyright…
Fig. 6.1 Pituitary macroadenoma (arrows) abutting the optic chiasm superiorly on contrast-enhanced coronal (a) and sagital (b) MRIs Other evaluations during his hospitalization revealed evidence of cardiomyopathy that was attributed…
© Springer Science+Business Media New York 2015Terry F. Davies (ed.)A Case-Based Guide to Clinical Endocrinology10.1007/978-1-4939-2059-4_5 5. Introduction David S. Cooper1 (1) Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, 1830 E. Monument…
It was noted above that the business case process is usually iterative and therefore the associated documentation is ‘live’: there must be a stipulated structure which facilitates formal change control…
