Diagnostic Imaging and Laparoscopy
Fig. 6.1 Coronal contrast-enhanced computed tomography (CT) image showing (a) multiple nodules with a diameter > 5 mm diffusely involving the tunica serosa over bowel loops and paracolic gutters (arrows),…
Peritoneal Carcinomatosis from Ovarian Cancer
Setting Study [Reference] No. Residual disease Survival Primary cytoreduction 5-year (%) Median (months) Hoskins (1994) [5] 41 R 0 60 62 ≤1 cm 35 77 >1 cm 20–35 Chi (2006)…
Rationale for Integrated Procedures: Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Combined
Gompertzian growth kinetics Fig. 8.1 Fig. 8.2 Norton-Simon hypothesis: progressive improvements in drug response do not change actual cancer survival 8.2 Intraperitoneal Chemotherapy: Physical and Biological Principles The pharmacological rationale…
Peritoneal Carcinomatosis from Colorectal Cancer
• T stage of primary (T4) • Lymph-node status (N1-2) • Mucinous/signet-ring-cell histology • Right-sided tumors • Positive peritoneal cytology • Emergency/nonradical surgery • Perforated/ruptured primary • Ovarian metastases •…
Peritoneal Mesothelioma
Types Subtypes Percentage Malignant Epithelial 75 Tubulopapillary nonglandular (solid) 13 Sarcomatous 6 Biphasic (mixed) 6 Undifferentiated Very rare Desmoplastic Very rare Lymphohistiocytic Very rare Small cell Very rare Deciduoid Very…
Patient Selection for Treatment
Fig. 13.1 Peritoneal carcinomatosis from ovarian cancer: involvement of lesser omentum and hepatoduodenal ligament Fig. 13.2 Lesser omentectomy and stripping of the omental bursa floor Another challenging problem, especially in…
Other Secondary Peritoneal Surface Malignancies
Patient Age Sex Primary HIPEC PCI CC FU Surv 1 72 M Sarcoma Oxal 20 1 DOD 12 2 77 F Sarcoma Oxal 16 0 AWD 11 3 61 M…
Classification of Intraperitoneal Spread
, Francesca Guerini, Andrea Zanoni and Giovanni de Manzoni (1) Department of Surgery, Upper G.I. Surgery Unit, Borgo Trento Hospital, Verona, Italy 5.1 Introduction An accurate staging system for cancer diseases aims at…
Peritoneal Carcinomatosis from Gastric Cancer
Study [Reference] Year Patients Drug Temperature (°C) Duration Mortality Morbility Survival Yan et al. [22] 2007 34 CDDP 120 mg + MMC 30 mg 42.5–43.5 60–90 – 14.7% 3 yrs…
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Techniques
Fig. 10.1 Hyperthermic intraperitoneal chemotherapy (HIPEC): peritoneal cavity expander. (Courtesy of Prof. Angelo Di Giorgio) A roller pump forces chemotherapy perfusion into the abdomen through the Tenckhoff catheter and extracts…
