Fig. 7.1 Classification of CLRs by intracellular signaling motifs. Representative CLRs are classified based on their intracellular signaling motifs: ITAM-containing receptors (such as Dectin-1, CLEC2, CLEC9A, and SIGN-R3), adaptor-recruiting receptors…
Year Author No. of patients Setting for DCs Responses 2002 Ladhams et al. 2 GM-CSF/IL-4 DC + tumor 1/2 inhibition of tumor growth 2003 Iwashita et al. 10 GM-CSF/IL-4 DC + tumor lysate + TNF-α + KLH 1/10…
History Parameter Action Age/family history Obesity BMI Avoid further gain, gradual loss Diabetes HbA1C/Fasting glucose Initiate diabetic therapy Inactivity Minutes of recreational physical activity/week Encourage 150 min or more recreational…
Fig. 17.1 Conceptual framework for receipt of optimal cancer care (Adapted from Shavers and Brown, JNCI 2002 with permission) After the initial treatment decisions are made, and treatments are underway,…
Physical and medical challenges Managing physical symptoms and side effects (e.g., pain, fatigue) Dealing with constant or changing treatment schedules Accepting stable disease as a desirable outcome of treatment Maintaining…
Fig. 3.1 Projected cases of all invasive cancers in the United States by age and sex [Reproduced with permission from Smith et al. (2009)] Although breast cancer is associated with…
Fig. 5.1 Model for explaining the influence of cancer and its treatments on common behavioral alterations including fatigue and cognitive dysfunction [Reproduced with permission from Miller et al. (2008)] These…
Reproductive stage (STRAW) Known physiology Behavioral correlates Known predictors of menopause transition or behavioral correlates Reproductive early to late Normal to elevated FSH Menstrual cycles obtain regularity; later AMH drops…
If current age is The probability of developing breast cancer in the next 10 years is (in %) Or 1 in: 20 0.06 1,732 30 0.44 228 40 1.45 69…
Fig. 15.1 Trajectories of distress in the first year after breast cancer diagnosis (N = 171; Henselmans et al. 2010). Predicted (solid lines) and observed (dashed lines) levels of distress are displayed….
