Fig. 1 (a) Formation of OSCs upon chewing/crushing of whole garlic cloves. (b) Chemical structures of commonly studied OSCs that are produced from allicin 3 Pharmacological Attributes of OSCs in…
miRNA Up/downregulated by CDF Reference(s) Let-7s Upregulated Ali et al. (2012) and Bao et al. (2012d) miR-21 Downregulated Roy et al. (2013), Bao et al. (2011, 2012b, c) and Ali…
Fig. 1 Developing a prostate cancer chemoprevention cocktail. Cancer is as diverse as the individual is and therefore needs a personalized rather than a generalized approach. Also, carcinogenesis is a…
Bishayee A (2009) Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev Res (Phila) 2:409–418CrossRef Bosetti C, Filomeno M, Riso P, Polesel J, Levi F,…
Watson J (2013) Oxidants, antioxidants and the current incurability of metastatic cancers. Open Biol 3:120144CrossRef
Start small but start immediately Identify a process to improve Plan Define performance metrics and collect baseline data Do Develop and implement an action plan Study Review the results of…
Fig. 2.1 Incidence/mortality of CRC and screening uptake rates over time. CRC incidence/mortality reported as rates among adults age 50 or older (Surveillance, Epidemiology and End Results database) to reflect…
Fig. 3.1 Discounted costs and discounted life-years gained per 1000 65-year-olds for 14 CRC screening strategies including two strategies for CT-colonography (CTC)* and the efficient frontier connecting the efficient strategies—Microsimulation…
Fig. 6.1 a Multi-target sDNA sensitivity by colorectal cancer (CRC) stage. Sensitivity for screenrelevant CRC (stages I—III) was 97 % overall (74 of 76), 100 % for lesions at or proximal to…
FIT Positivity (%) Sensitivity (%) Specificity (%) Manufacturers’ quoted fecal hemoglobin cutoff (ng Hb/mL buffer) A 6.4 29.8 96.7 50 B 11.0 30.5 92.9 40 C 22.3 53.2 81.8 10 D…
