in the Development of Black Seed-Derived Anticancer Agents
Fig. 1 Figure shows a timeline of the various periods (over the last 3000–4000 years) of Black seed use that has led to the discovery of Thymoquinone. The first description…
Role of Chemokine Receptor Signaling Axis and Natural Bioactive Chemopreventive Agents in Metastasis of Breast Cancer
Fig. 1 Schematic overview of CXCR4-SDF-1α-induced intracellular signal transduction pathway and desensitization of activated receptor signaling Since SDF-1α is constitutively expressed, it has been reported that shutting off continuous stimulation…
Bacteria in Patients Treated with Chemotherapy and Radiation Therapy
Trial numbera Objectives Patient population Intervention Stage of trial Country NCT01473290 Prevention of gastrointestinal complication Cancer patients treated by chemotherapy or radiation therapy to pelvic region VSL#3 (mixture of probiotic…
Factors and Breast Cancer
Ahern TP, Pedersen L, Tarp M et al (2011) Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study. J Natl Cancer Inst 103:1461–1468 Alexander DD, Morimoto…
Isoflavones in the Breast Cancer Risk: From Preclinical Findings to Clinical Strategy
Fig. 1 Molecular targets of genistein on cancer cells. Genistein exhibits either stimulatory or inhibitory effects on different signaling pathways. Abbreviations: COX-2 cyclooxygenase-2, FAK focal adhesion kinase, HIF-1α hypoxia-inducible factor…
Role of Energy Balance in Cancer Prevention
Ahmed RL, Schmitz KH, Anderson KE, Rosamond WD, Folsom AR (2006) The metabolic syndrome and risk of incident colorectal cancer. Cancer 107:28–36 Alberti KGMM, Zimmet P, Shaw J (2006) Metabolic…
for Sesame Seed-Derived Factors to Prevent Colorectal Cancer
Fig. 1 Chemical structure of potential anticancer factors from sesame seed and proposed underlying mechanisms for the suppression of polyp formation in Min mice by Sesamol. Ferulic acid, sesamin, sesamolin,…
Role of Dietary Polyphenols in Prostate Cancer Chemoprevention
Fig. 1 Polyphenolic phytochemicals in prevention of prostate cancer 2 Epigallocatechin-3-Gallate Epigallocatechin-3-gallate (EGCG) represents the major polyphenol constituent present in green tea, the most popular beverage next to water. The…
Role of Organosulfur Compounds Derived From Allium Vegetables in Cancer Prevention and Therapy
Fig. 1 (a) Formation of OSCs upon chewing/crushing of whole garlic cloves. (b) Chemical structures of commonly studied OSCs that are produced from allicin 3 Pharmacological Attributes of OSCs in…
on the Promising Anticancer Activity of CDF, a Synthetic Curcumin Analogue
miRNA Up/downregulated by CDF Reference(s) Let-7s Upregulated Ali et al. (2012) and Bao et al. (2012d) miR-21 Downregulated Roy et al. (2013), Bao et al. (2011, 2012b, c) and Ali…
