© Springer Science+Business Media New York 2015Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar, Emad A. Rakha and Dina Kandil (eds.)Precision Molecular Pathology of Breast CancerMolecular Pathology Library1010.1007/978-1-4939-2886-6_16 16. Molecular Pathology of Breast Cancer Metastasis Mohammed A. Aleskandarany1,…
Fig. 8.1 Immunohistochemical staining of estrogen receptor showing granular/punctate brown nuclear staining in consistent with false positive pattern [55] Predictive Value of Hormone Receptor Expression in Breast Cancer A factor is…
Fig. 14.1 Schematic representation biphasic progression of fibroepithelial tumors PT is further classified into benign, borderline and malignant categories. Due to some overlapping histologic features, differentiation of FA and benign PT…
© Springer Science+Business Media New York 2015Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar, Emad A. Rakha and Dina Kandil (eds.)Precision Molecular Pathology of Breast CancerMolecular Pathology Library1010.1007/978-1-4939-2886-6_10 10. Molecular Classification of Breast Cancer Mohammed A. Aleskandarany1, Ian O. Ellis1…
Gene Name Location Function TP53 Tumor protein 53 17p13.1 Tumor suppressor PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase 3q26.32 Cell growth, division and survival AKT1 v-akt murine thymoma viral oncogene homolog 1 14q32.32 Cell…
Fig. 3.1 H&E section from a mixed culture of fibroblast, breast epithelial cells and myoepithelial cells grown in a 3D collagen 1 matrix. Note particularly the organisation of clear myoepithelial cells…
© Springer Science+Business Media New York 2015Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar, Emad A. Rakha and Dina Kandil (eds.)Precision Molecular Pathology of Breast CancerMolecular Pathology Library1010.1007/978-1-4939-2886-6_12 12. Molecular-Based Diagnostic, Prognostic and Predictive Tests in…
© Springer Science+Business Media New York 2015Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar, Emad A. Rakha and Dina Kandil (eds.)Precision Molecular Pathology of Breast CancerMolecular Pathology Library1010.1007/978-1-4939-2886-6_4 4. Molecular Pathology of Precancerous Lesions of the…
7 Relation to life expectancy, functional dependence, and tolerance to stress Relation to life expectancy and tolerance to stress Relation to life expectancy and dependence Relation to survival; may indicate…
Study Patients Chemotherapy type Time of assessment Age Cognitive assessment Results Mayerhofer et al. [27] Patients with advanced ovarian cancer (n = 28) Paclitaxel/carboplatin Before CT, after cycle 3, and after CT…
