Hodgkin Lymphoma
Age group (years) Incidence of Hodgkin lymphoma in the United Statesa Percent Hodgkin lymphoma of all cancers Estimated number of annual new cases of Hodgkin lymphoma Males Females Males (%)…
Surgery: Treatment of Oligometastatic Disease
Fig. 13.1 A D1 solitary osteolytic metastasis; the 56-year- old patient underwent en bloc vertebrectomy and reconstruction with homoplastic diaphysis segment filled with the autoplastic morcellized bone, plates, and screws;…
Detection of Bone Metastases and Evaluation of Therapy Response in Prostate Cancer Patients by Radiolabelled Choline PET/CT
Fig. 7.1 Pathway of choline metabolism in normal and cancer cell (Cho choline, ChAT choline acetyltransferase, ACho acetylcholine, ChoK choline kinase, CMP cytidylate, DAG diacylglycerol, PCho phosphocholine, CDP diphosphocholine, PPi…
New Radiopharmaceutical Markers for Metabolism and Receptor
Fig. 9.1 18F-FACBC positive bone metastases in high-risk prostate cancer at staging evaluation. A 71-year-old patient diagnosed with high-risk prostate cancer (PSA 6.8 ng/ml; cT2; GS 4 + 4) underwent…
Approaches for Assessment of Response of Bone Metastases to Therapies
Fig. 18.1 Signs of responding vertebral metastases visible on T1w MR imaging (Modified from Lecouvet et al. [31]) 1. Shrinkage or progressive fading of the marrow signal intensity abnormalities …
Nuclear Medicine Modalities to Image Bone Metastases with Bone-Targeting Agents: Conventional Scintigraphy and Positron-Emission Tomography
Fig. 6.1 Prostate cancer patient with increased PSA level after radical prostatectomy. (a) 99mTc-MDP planar whole-body bone scan in anterior (left) and posterior (right) views shows multiple increasing tracer uptakes…
Imaging of Glycolysis with 18F-FDG PET
Fig. 8.1 Physiopathological processes correlate with the entrance of FDG in the prostatic cancer cell. DHT dihydrotestosterone, AR androgen receptors, TCA tricarboxylic acid cycle 8.2 Comparative Diagnostic Accuracy among Imaging…
Bone Metastases from Prostate Cancer: From Symptom Control to Pain Palliation
Syndrome Pain Cranial nerve involved Orbital Retro-supraorbital II visual loss III, IV, VI diplopia V frontal sensory loss Cavernous sinus Supraorbital frontal III, IV, VI diplopia V sensory loss Middle…
Bone Metastases from Prostate Cancer: Hormonal Therapy
Therapy Mechanism of action Side effects LH-RH agonists (buserelin, goserelin, leuprolide, and triptorelin) Downregulation of LH-RH receptor Flushes, weight increase, impotence, loss of libido, fatigue, decreased muscle mass, osteoporosis, anemia,…
Bone Homing and Metastasis
Fig. 3.1 Bone metastasis of high-grade prostate cancer Fig. 3.2 Bone metastasis of prostate cancer. The neoplastic cells are immunostained with antibody against prostein Understanding the mechanisms by which PCa…
