Groups for Survival in HPV-Positive and HPV-Negative OPSCC
Fig. 1 Classification of risk groups for survival of OPSCC using RPA analysis of 2 RTOG trials by Ang et al. (2010) In 2013, Rietbergen et al. conducted a study, based…
Role of Conventional Surgery in Oropharyngeal Cancer
Fig. 1 Treatment options of oropharyngeal cancer An important concept in selecting a surgical approach is to develop a clear “concept of operation”. This means that the surgeon selects the most…
Patterns and Biology of HPV-Associated HNSCC
First author Year Anatomical site HPV- HPV+ Differently expressed genes (probes) Analyzed genes (probes) Oropharynx Oral cavity Tonsils Base of tongue/tongue Larynx Hypopharynx Keck 2014 X X X 75 55…
Expectations in HNSCC
Cervarix Gardasil Gardasil 9 HPV coverage 16, 18 6, 11, 16, 18 6, 11, 16, 18, 31, 33, 45, 52, 58 Manufacturer GlaxoSmithKline Merck Merck Producing cells Trichoplusia ni…
of HPV Subtypes with Focus on HPV-Infection and Cancer in the Head and Neck Region
Fig. 1 Phylogenetic tree of the HPV16 variants identified by Yamada et al. (1995) in the United States within a sample of 30 HPV16 isolates based on parsimony analysis. Combined sequences…
on De-intensification and Intensification Studies in HPV
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_20 Update on De-intensification and Intensification Studies in HPV Hisham Mehanna1, 2 (1)…
Immunology and HPV
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_19 Cancer Immunology and HPV Barbara Wollenberg1 (1) Department of Otorhinolaryngology, University of…
Factors for Outcome and Quality of Life in HPV-Positive and HPV-Negative HNSCC
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_18 Predictive Factors for Outcome and Quality of Life in HPV-Positive and…
We De-escalate the Treatment for HPV-Positive Tumors?
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_13 Should We De-escalate the Treatment for HPV-Positive Tumors? Andreas Dietz1, 2 , Gunnar Wichmann1,…
Radiotherapy in HPV-Associated Oropharyngeal Cancer Patients
Fig. 1 NTCP values (risk on side effects) according to the 6 different approaches. CRT-70 current standard chemoradiation; BioRT-70 standard radiotherapy with cetuximab; CRT-56 reduced radiation dose chemoradiation; CPT-70 standard radiation…
