Specificity activation Non-specific (activate systemic immunity, relatively old) Specific (target cancer cells or cancer-specific antigens, relatively old) Active immunization (to elicit immunity in vivo) Biological response modifier Cancer vaccine Dendritic…
Fig. 17.1 (a) Institutions where end-of-life care was provided [33]. (b) Waiting periods for transfer to a palliative care unit [33] Fig. 17.2 (a) Treatment modalities for managing ascites (multiple…
Fig. 3.1 The major morphological types of epithelial ovarian tumors and the mimic normal epithelia; (a and b) fallopian tubal epithelium (a) and serous carcinoma (b); (c and d) endometrium…
Fig. 10.1 Treatment of malignant sex cord-stromal tumors. *Fertility-preserving surgery—affected-side salpingo-oophorectomy + omentectomy + peritoneal cytology + detailed intra-abdominal examination. **Lymph node dissection (biopsy) can be omitted. Reprint with permission from ref. 21 10.3 Malignant Ovarian…
Fig. 16.1 Cycle of frailty [66], reprinted with permission of Oxford University Press Fig. 16.2 Hypothesized molecular and physiological association with frailty [67], reprinted with permission of John Wiley and…
Fig. 14.1 Treatment strategy of recurrent epithelial ovarian cancer Table 14.1 Important clinical trials for recurrent ovarian cancer Study (y) Drug n Primary endpoint RR(%) PFS(M) OS(M) Comments Platinum-sensitive disease…
Fig. 12.1 The history of primary chemotherapy for epithelial ovarian cancer In contrast to paclitaxel, fractionated weekly dosing of carboplatin remains a challenging regimen. The Multicentre Italian Trials in Ovarian…
Author Year Number of patients Positive rate(%) Stage (%) Positive rate(%) la lb lc PEN PAN Sakuragi, et al 2000 78 5.1 3.2 – 6.4 0 5.1 Suzuki, et al…
High-grade serous Low-grade serous High-grade endometrioid Low-grade endometrioid Clear cell Mucinous Unspecified carcinoma No. 1501 70 64 14 58 16 166 BRCA1 (%) 10.3 4.3 6.3 0 6.9 0…
Fig. 8.1 Flowchart of fundamental strategies for the management of epithelial ovarian cancer. Cited from Komiyama et al. [3] with slight modifications 8.2 Surgical Management 8.2.1 Early (Localized to the Ovary)-Staged…
