Proton therapy for hematologic malignancies

Aug 6, 2020 by in ONCOLOGY Comments Off on Proton therapy for hematologic malignancies

Introduction As early as the 1970s, proton therapy was considered a promising treatment for hematologic malignancies, specifically for use in total nodal irradiation, the historic standard of care treatment for…

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Head and neck

Aug 6, 2020 by in ONCOLOGY Comments Off on Head and neck

Introduction Radiation therapy, whether used as definitive treatment or as an adjuvant to surgery, is an essential component of treatment for many patients with head and neck cancer (HNC). Both…

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Proton therapy for prostate cancer

Aug 6, 2020 by in ONCOLOGY Comments Off on Proton therapy for prostate cancer

Introduction The use of proton therapy for the treatment of cancer was first proposed by Robert Wilson in 1946. A beam of protons gives most of its dose at a…

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Proton therapy for gynecologic malignancies

Aug 6, 2020 by in ONCOLOGY Comments Off on Proton therapy for gynecologic malignancies

Introduction Each year more than 90,000 women are diagnosed with a gynecologic (ovarian, vulvar, vaginal, cervical, uterine, fallopian tube, or primary peritoneal) cancer in the United States. Radiotherapy is often…

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Physics quality assurance

Aug 6, 2020 by in ONCOLOGY Comments Off on Physics quality assurance

Introduction This chapter describes the physics quality assurance (QA) program for the proton pencil beam scanning (PBS) gantry of the Hitachi ProBeat machine (Hitachi America, Ltd., Tarrytown, NY) at the…

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Immobilization and simulation

Aug 6, 2020 by in ONCOLOGY Comments Off on Immobilization and simulation

Introduction Intensity-modulated proton therapy (IMPT) using pencil beam scanning (PBS) technology is advancing rapidly for delivering precise and more conformal doses to target volumes while sparing surrounding normal and critical…

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Proton radiotherapy for breast cancer

Aug 6, 2020 by in ONCOLOGY Comments Off on Proton radiotherapy for breast cancer

Introduction Numerous planning studies demonstrate superior dosimetry for proton radiotherapy compared with photon-based radiotherapy for breast cancers of all stages, even compared with intensity-modulated radiotherapy. Protons can reduce dose to…

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Adult central nervous system tumors

Aug 6, 2020 by in ONCOLOGY Comments Off on Adult central nervous system tumors

Introduction For both primary and metastatic brain tumors, radiation therapy (RT) remains one of the standard treatment modalities. Although RT techniques using photons have greatly improved in recent decades, substantial…

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Intensity-modulated proton therapy patient treatments

Aug 6, 2020 by in ONCOLOGY Comments Off on Intensity-modulated proton therapy patient treatments

Introduction Intensity-modulated proton therapy (IMPT) can begin only after a number of other processes have been completed, including simulation and treatment planning. For both proton and photon treatments, radiation oncology…

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