Abstract This chapter describes the causes, clinical manifestations, diagnosis and treatment of various types of both acquired and inherited bone marrow failure syndromes. Keywords Diamond–Blackfan anemia (DBA), Fanconi anemia (FA),…
Abstract Iron deficiency is the most common nutritional deficiency in children and is worldwide in distribution, affecting 2 billion people. The prevalence of iron deficiency worldwide is twice as high…
Abstract Anemia during the neonatal period is caused by: (i) Hemorrhage : acute or chronic, (ii) Hemolysis : congenital hemolytic anemias or due to isoimmunisation, and (iii) Failure of red…
Abstract Lymphadenopathy and splenomegaly are common findings in children. Both benign and malignant processes can produce these findings and it is important to distinguish between the two so that appropriate…
Abstract Anemia can be defined as a reduction in hemoglobin concentration, hematocrit, or number of red blood cells per cubic millimeter. The lower limit of the normal range is set…
Abstract A variety of systemic illnesses including acute and chronic infections, neoplastic diseases, connective tissue disorders, and storage diseases are associated with hematologic manifestations. Keywords Systemic illness, hematology, iron deficiency,…
Abstract Over the past several years, molecular diagnostic testing in patients with hematologic and oncologic disorders has become increasingly sophisticated and prevalent. While in the past focused genetic tests were…
