Variant class Pathogenicity 1 Pathogenic 2 Likely pathogenic 3 Uncertain significance 4 Likely benign 5 Benign Mutations may be described as either constitutional or somatic. Constitutional mutations are also known…
Pro Contra In vivo sensitivity testing Fear of patients to leave the tumour in place Strong prognostic value of pCR Discrepancy in grading for core biopsy and definite specimen: risk…
Fig. 24.1 Algorithm summarizing standard axillary management 24.2.2 Preoperatively Detected Axillary Metastases A direct AC without SLNB remains the standard of care in clinically node-positive breast cancer patients, with preoperatively detected…
Mastectomy Removal of the totality of the glandular breast tissue (as opposed to breast-conserving surgery) Radical mastectomy (Halsted) Removal of the totality of the glandular breast tissue, overlying skin, nipple-areola…
Fig. 61.1 The Cassandra data set (Reproduced from Ref. 14 with permission from Prof Alison Leary FRCN) The clinical domains of a CNS can be seen in detail in ◘ Table…
Fig. 59.1 Four-category model of attachment Each mental model varies from positive (trust in others: confidence in self) to negative (distrust of others: anxiety about self) and shapes individuals’ expectations…
© Springer International Publishing AG 2018Lynda Wyld, Christos Markopoulos, Marjut Leidenius and Elżbieta Senkus-Konefka (eds.)Breast Cancer Management for Surgeonshttps://doi.org/10.1007/978-3-319-56673-3_58 58. Breast Cancer Survivorship: Chronic Post-operative Pain and Sensory Changes Tuomo J. Meretoja1 (1) Comprehensive Cancer Center, Breast Surgery Unit,…
Khorana score for short-term risk of VTE Points Type of cancer Stomach, pancreas Lung, lymphoma, gynaecologic, bladder, testis Others 2 1 0 Platelet count <350 × 109/l ≥350 × 109/l 0 1 Haemoglobin ≥10 g/dl…
Fig. 26.1 Split mapping of the drainage of the arm and the breast. SLN and ARM node The original ARM technique [10, 11] was performed by injecting 1–5 mL of blue dye…
Fig. 47.1 Axial T2-weighted magnetic resonance imaging (MRI) image showing desmoid fibromatosis (DF) of the left breast of a 28-year-old female with bilateral breast implants in situ (2 years post…
