Tumor suppressor genes
Tumor suppressor genes David Cosgrove, MB, BCh Ben Ho Park, MD, PhD Bert Vogelstein, MD Overview Cancer is a genetic disease. Mutations and other alterations in growth promoting genes (oncogenes)…
Molecular diagnostics in cancer
Molecular diagnostics in cancer Roshni D. Kalachand, MBBCh, MD Bryan T. Hennessy, MD Robert C. Bast Jr. MD Gordon B. Mills, MD, PhD Overview Molecular diagnostics refers to the use…
Differentiation therapy
Differentiation therapy Sai-Juan Chen, MD, PhD Xiao-Jing Yan, MD Guang-Biao Zhou, MD Zhu Chen, PhD Overview Abnormal differentiation is one of the main features of human cancers, especially in hematological…
